Pubblicazioni

ELENCO DELLE PUBBLICAZIONI DELLA PROF:SSA LACIVITA NEL TRIENNIO 2019-2017.

1. Vigli D, Rusconi L, Valenti D, La Montanara P., Cosentino L, Lacivita E, Leopoldo M, Amendola E, Gross C, Landsberger N, Laviola G, Kilstrup-Nielsen C, Vacca RA., De Filippis B. Rescue of prepulse inhibition deficit and brain mitochondrial dysfunction by pharmacological stimulation of the central serotonin receptor 7 in a mouse model of CDKL5 Deficiency Disorder. Neuropharmacol. 2019, 144:104-114.

2. Modica MN, Lacivita E, Intagliata S, Salerno L, Romeo G, Pittalà V, Leopoldo M. Structure-Activity Relationships and Therapeutic Potentials of 5-HT7 Receptor Ligands: An Update. J Med Chem. 2018, 61:8475-8503.

3. Arreola-Peralta LD, Altamirano-Reyna F, Galindo-González DM, Solis-Anguiano JG, Lacivita E, Leopoldo M, Terrón JA. Potentiation of capsaicin-induced neurogenic inflammation by 5-HT7 receptors in the rat hind paw: Involvement of calcitonin gen-related peptide. Peptides. 2018, 105:1-6.

4. Podlewska S, Kafel R, Lacivita E, Satała G, Kooistra AJ, Vass M, de Graaf C, Leopoldo M, Bojarski AJ, Mordalski S. Structural insights into serotonin receptor ligands polypharmacology. Eur J Med Chem. 2018, 151:797-814.

5. Lucente E, Liu H, Liu Y, Hu X, Lacivita E, Leopoldo M, Cheng Z. Novel 64Cu Labeled RGD2-BBN Heterotrimers for PET Imaging of Prostate Cancer. Bioconjug Chem. 2018, 29(5):1595-1604.

6. Carbone C, Adinolfi A, Cinque S, Lacivita E, Alleva E, Leopoldo M, Adriani W. Activation of 5-HT7 receptor by administration of its selective agonist, LP-211, modifies explorative-curiosity behavior in rats in two paradigms which differ in visuospatial parameters. CNS Neurosci Ther. 2018, doi: 10.1111/cns.12812.

7. Stama ML, Ślusarczyk J, Lacivita E, Kirpotina LN, Schepetkin IA, Chamera K, Riganti C, Perrone R, Quinn MT, Basta-Kaim A, Leopoldo M. Novel ureidopropanamide based N-formyl peptide receptor 2 (FPR2) agonists with potential application for central nervous system disorders characterized by neuroinflammation. Eur J Med Chem. 2017, 141:703-720.

8. Lacivita E, Perrone R, Margari L, Leopoldo M. Targets for Drug Therapy for Autism Spectrum Disorder: Challenges and Future Directions. J Med Chem. 2017, 60(22):9114-9141.

9. Stama ML, Lacivita E, Kirpotina LN, Niso M, Perrone R, Schepetkin IA, Quinn MT, Leopoldo M. Functional N-Formyl Peptide Receptor 2 (FPR2) Antagonists Based on the Ureidopropanamide Scaffold Have Potential To Protect Against Inflammation-Associated Oxidative Stress. ChemMedChem. 2017, 12(22):1839-1847.

10. Beaudet G, Paizanis E, Zoratto F, Lacivita E, Leopoldo M, Freret T, Laviola G, Boulouard M, Adriani W. LP-211, a selective 5-HT7 receptor agonist, increases novelty-preference and promotes risk-prone behavior in rats. Synapse. 2017, 71(12).

11. Santello M, Bisco A, Nevian NE, Lacivita E, Leopoldo M, Nevian T. The brain-penetrant 5-HT7 receptor agonist LP-211 reduces the sensory and affective components of neuropathic pain. Neurobiol Dis. 2017, 106:214-221.

12. Valenti D, de Bari L, Vigli D, Lacivita E, Leopoldo M, Laviola G, Vacca RA, De Filippis B. Stimulation of the brain serotonin receptor 7 rescues mitochondrial dysfunction in female mice from two models of Rett syndrome. Neuropharmacology. 2017, 121:79-88.

13. Speranza L, Labus J, Volpicelli F, Guseva D, Lacivita E, Leopoldo M, Bellenchi GC, di Porzio U, Bijata M, Perrone-Capano C, Ponimaskin E. Serotonin 5-HT7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons. J Neurochem. 2017, 141(5):647-661.

14. Lacivita E, Lucente E, Kwizera C, Antunes IF, Niso M, De Giorgio P, Perrone R, Colabufo NA, Elsinga PH, Leopoldo M. Structure-activity relationship study towards non-peptidic positron emission tomography (PET) radiotracer for gastrin releasing peptide receptors: Development of [18F] (S)-3-(1H-indol-3-yl)-N-[1-[5-(2-fluoroethoxy)pyridin-2-yl]cyclohexylmethyl]-2-methyl-2-[3-(4-nitrophenyl)ureido]propionamide. Bioorg Med Chem. 2017, 25(1):277-292.

15. Carrieri A, Lacivita E, Belviso BD, Caliandro R, Mastrorilli P, Gallo V, Niso M, Leopoldo M. Structural Determinants in the Binding of BB2 Receptor Ligands: In Silico, X-Ray and NMR Studies in PD176252 Analogues. Curr Top Med Chem. 2017, 17(14):1599-1610.