Pubblicazioni

Autore di 46 pubblicazioni internazionali peer-reviewed
  1. Maugeri A, Lombardo GE, Cirmi S, Süntar I, Barreca D, Laganà G, Navarra M. Pharmacology and toxicology of tannins. Arch Toxicol. 2022; 96(5):1257-1277.
  2. Versace AG, Bitto A, Ioppolo C, Aragona CO, La Rosa D, Roberts WN, D’Angelo T, Cinquegrani A, Cirmi S, Irrera N, Navarra M, Corrao S, Gangemi S, Bagnato G. IL-13 and IL-33 Serum Levels Are Increased in Systemic Sclerosis Patients With Interstitial Lung Disease. Front. Med. 2022, 9:825567.
  3. Cirmi S, Maugeri A, Russo C, Musumeci L, Navarra M, Lombardo GE. Oleacein Attenuates Lipopolysaccharide-Induced Inflammation in THP-1-Derived Macrophages by the Inhibition of TLR4/MyD88/NF-κB Pathway. Int. J. Mol. Sci. 2022, 23, 1206.
  4. Maugeri A, Lombardo GE, Navarra M, Cirmi S*, Rapisarda A. The chorioallantoic membrane: A novel approach to extrapolate data from a well-established method. J Appl Toxicol., 2021. doi: 10.1002/jat.4271. 
  5. Cirmi S, Maugeri A, MIcali A, Marini HR, Puzzolo D, Santoro G, Freni J, Squadrito F, Irrera N, Pallio G, Navarra M, Minutoli L. Cadmium-Induced Kidney Injury in Mice Is Counteracted by a Flavonoid-Rich Extract of Bergamot Juice, Alone or in Association with Curcumin and Resveratrol, via the Enhancement of Different Defense Mechanisms. Biomedicines, 2021, 9(12):1797. 
  6. Mantuano P, Boccanegra B, Conte E, De Bellis M, Cirmi S, Sanarica F, Cappellari O, Arduino I, Cutrignelli A, Lopedota AA, Mele A, Denora N, De Luca A. β-Dystroglycan Restoration and Pathology Progression in the Dystrophic mdx Mouse: Outcome and Implication of a Clinically Oriented Study with a Novel Oral Dasatinib Formulation. Biomolecules,. 2021, 11(11):1742. 
  7. Russo C, Maugeri A, Lombardo GE, Musumeci L, Barreca D, Rapisarda A, Cirmi S*, Navarra M. The Second Life of Citrus Fruit Waste: A Valuable Source of Bioactive Compounds. Molecules, 2021,26(19):5991. 
  8. Adorisio S, Argentieri MP, Avato P, Caderni G, Chioccioli S, Cirmi S, Delfino DV, Greco G, Hrelia P, Iriti M, Lenzi M, Lombardo GE, Luceri C, Maugeri A, Montopoli M, Muscari I, Nanì MF, Navarra M, Gasperini S, Turrini E, Fimognari C. The molecular basis of the anticancer properties of quercetin. Pharmadvances, 2021, 3 (3): 496-520.
  9. Abbate F*, Maugeri A, Laurà R, Levanti M, Navarra M, Cirmi S*, Germanà A. Zebrafish as a useful model to study oxidative stress-linked disorders: focus on flavonoids. Antioxidant, 2021, 10(5), 668.
  10. Ferlazzo N, Micali A, Marini HR, Freni J, Santoro G, Puzzolo D, Squadrito F, Pallio G, Navarra M, Cirmi S*, Minutoli L. A flavonoid-rich extract from bergamot juice, alone or in association with curcumin and resveratrol, shows protective effects in a murine model of cadmium-induced testicular injury. Pharmaceuticals, 2021, 14(5), 386.
  11. Maugeri A, Lombardo GE, Musumeci L, Russo C, Gangemi S, Calapai G, Cirmi S*, Navarra M. Bergamottin and 5-geranyloxy-7-methoxycoumarin cooperate in the cytotoxic effect of Citrus bergamia (bergamot) essential oil in human neuroblastoma SH-SY5Y cell line. Toxins, 2021, 13(4), 275.
  12. Cirmi S, Maugeri A, Lombardo GE, Russo C, Musumeci L, Gangemi S, Calapai G, Barreca D, Navarra M. A Flavonoid-Rich Extract of Mandarin Juice Counteracts 6-OHDA-Induced Oxidative Stress in SH-SY5Y Cells and Modulates Parkinson-Related Genes. Antioxidants, 2021, 10(4):539.
  13. Montalbano G, Maugeri A, Guerrera MC, Miceli N, Navarra M, Barreca D, Cirmi S*, Germanà A. A White Grape Juice Extract Reduces Fat Accumulation through the Modulation of Ghrelin and Leptin Expression in an In Vivo Model of Overfed Zebrafish. Molecules, 2021, 26(4):1119.
  14. Kubica P, Szopa A, Kokotkiewicz A, Miceli N, Taviano MF, Maugeri A, Cirmi S, Synowiec A, Gniewosz M, Elansary HO, Mahmoud EA, El-Ansary DO, Nasif O, Luczkiewicz M, Ekiert H. Production of Verbascoside, Isoverbascoside and Phenolic Acids in Callus, Suspension, and Bioreactor Cultures of Verbena officinalis and Biological Properties of Biomass Extracts. Molecules, 2020, 25(23):5609.
  15. Lombardo GE, Cirmi S, Musumeci L, Pergolizzi S, Maugeri A, Russo C, Mannucci C, Calapai G, Navarra M. (2020). Mechanisms underlying the anti-inflammatory activity of bergamot essential oil and its antinociceptive effects. Plants (Basel), 2020, 9 (6): E704.
  16. Cirmi S, El Abd A, Letinier L, Navarra M, Salvo F. Cardiovascular Toxicity of Tyrosine Kinase Inhibitors Used in Chronic Myeloid Leukemia: An Analysis of the FDA Adverse Event Reporting System Database (FAERS). Cancers, 2020, 12(4):E826.
  17. Cirmi S, Randazzo B, Russo C, Musumeci L, Maugeri A, Montalbano G, Guerrera MC, Lombardo GE, Levanti M. Anti-inflammatory effect of a flavonoid-rich extract of orange juice in adult zebrafish subjected to vibrio anguillarum-induced enteritis. Nat Prod Res, 2020, 1-4.
  18. Ferlazzo N, Cirmi S, Maugeri A, Russo C, Lombardo GE, Gangemi S, Calapai G, Mollace V, Navarra M. Neuroprotective effect of bergamot juice in 6-OHDA-induced SH-SY5Y cell death, an in vitro model of Parkinson’s disease. Pharmaceutics, 2020, 12(4):326.
  19. Cirmi S, Celano M, Lombardo GE, Maggisano V, Procopio A, Russo D, Navarra M. Oleacein inhibits STAT3, activates the apoptotic machinery and exerts anti-metastatic effects in the SH-SY5Y human neuroblastoma cells. Food and Function, 2020, 1(4):3271-3279.
  20. Musumeci L, Maugeri A, Cirmi S, Lombardo GE, Russo C, Gangemi S, Calapai G, Navarra M. Citrus fruits and their flavonoids in inflammatory bowel disease: an overview. Nat Prod Res, 2020, 34(1):122-136.
  21. Navarra M, Femia AP, Romagnoli A, Tortora K, Luceri C, Cirmi S, Ferlazzo N, Caderni G. A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer, the Pirc rat (F344/NTac-Apcam1137). Eur J Nutr, 2020, 59(3):885-894.
  22. Maugeri A, Cirmi S, Minciullo PL, Gangemi S, Calapai G, Mollace V, Navarra M. Citrus fruits and inflammaging: a systematic review. Phytochemistry Reviews, 2019, 18:1025–1049.
  23. Cirmi S, Ferlazzo N, Gugliandolo A, Musumeci L, Mazzon E, Bramanti A, Navarra M. Moringin from Moringa Oleifera seeds inhibits growth, arrests cell-cycle, and induces apoptosis of SH-SY5Y human neuroblastoma cells through the modulation of NF-κB and apoptotic related factors. Int J MolSci, 2019, 20(8). pii: E1930.
  24. Cirmi S, Navarra M, Woodside JV, Cantwell MM. Citrus fruits intake and oral cancer risk: a systematic review and meta-analysis. Pharmacol Res., 2018, pii: S1043-618(18)30472-9.
  25. Cirmi S, Maugeri A, Ferlazzo N, Gangemi S, Calapai G, Schumacher U, Navarra M. Anticancer Potential of Citrus Juices and Their Extracts: A Systematic Review of Both Preclinical and Clinical Studies. Front Pharmacol., 2017, 8:420.
  26. Mandalari G, Bisignano C, Cirmi S, Navarra M. Effectiveness of Citrus Fruits on Helicobacter pylori. Evid Based Complement Alternat Med., 2017, 2017:8379262.
  27. Fusco R, Cirmi S, Gugliandolo E, Di Paola R, Cuzzocrea S, Navarra M. A flavonoid-rich extract of orange juice reduced oxidative stress in an experimental model of inflammatory bowel disease. Journal of Functional Foods, 2017, 30: 168-178.
  28. Giofrè SV, Cirmi S, Mancuso R, Nicolò F, Lanza G, Legnani L, Campisi A, Chiacchio MA, Navarra M, Gabriele B, Romeo R. Synthesis of spiro[isoindole-1,5’-isoxazolidin]-3(2H)-ones as potential inhibitors of the MDM2-p53 interaction. Beilstein Journal Organic Chemistry, 2016, 2793–2807.
  29. Cirmi S, Ferlazzo N, Lombardo GE, Maugeri A, Calapai G, Gangemi S, Navarra M. Chemopreventive Agents and Inhibitors of Cancer Hallmarks: May Citrus Offer New Perspectives? Nutrients, 2016, 8(11). pii: E698.
  30. Pistone A, Iannazzo D, Ansari S, Milone C, Salamò M, Galvagno S, Cirmi S, Navarra M. Tunable doxorubicin release from polymer-gated multiwalled carbon nanotubes. Int J Pharm, 2016, 515(1-2):30-36.
  31. Cirmi S, Ferlazzo N, Lombardo GE, Ventura-Spagnolo E, Gangemi S, Calapai G, Navarra M. Neurodegenerative diseases: might Citrus flavonoids play a protective role? Molecules, 2016, 21(10). pii: E1312.
  32. Bagnato G, Roberts WN, Sciortino D, Sangari D, Cirmi S, Ravenell RL, Navarra M, Bagnato G, Gangemi S.  Mastocytosis and systemic sclerosis: a clinical association. Clin Mol Allergy, 2016, 14:13.
  33. Ferlazzo N, Cirmi S, Calapai G, Ventura-Spagnolo E, Gangemi S, Navarra M. Anti-inflammatory activity of Citrus bergamia derivatives: where do we stand? Molecules, 2016, 21(10). pii: E1273.
  34. Cirmi S, Bisignano C, Mandalari G, Navarra M. Anti-infective potential of Citrus bergamia Risso et Poiteau (bergamot) derivatives: a systematic review. Phytother. Res., 2016, 30(9):1404-11.
  35. Ferlazzo N, Visalli G, Cirmi S, Lombardo GE, Laganà P, Di Pietro A, Navarra M. Natural iron chelators: Protective role in A549 cells of flavonoids-rich extracts of Citrus juices in Fe3+-induced oxidative stress. Environ Toxicol Pharmacol., 2016, 43:248-256.
  36. Currò M, Risitano R, Ferlazzo N, Cirmi S, Gangemi C, Caccamo D, Ientile R, Navarra M. Citrus bergamia juice extract attenuates β-Amyloid-induced pro-inflammatory activation of THP-1 cells through MAPK and AP-1 pathways. Sci Rep., 2016, 6:20809.
  37. Ferlazzo N*, Cirmi S*, Russo M, Trapasso E, Ursino MR, Lombardo GE, Gangemi S, Calapai G, Navarra M. NF-κB mediates the antiproliferative and proapoptotic effects of bergamot juice in HepG2 cells. Life Sci., 2016, 146:81-91.
  38. Ferlazzo N, Visalli G, Smeriglio A, Cirmi S, Lombardo GE, Campiglia P, Di Pietro A, Navarra M. Flavonoid fraction of orange and bergamot juices protect human lung epithelial cells from hydrogen peroxide-induced oxidative stress. Evid Based Complement Alternat Med., 2015, 2015:957031.
  39. Filocamo A, Bisignano C, Ferlazzo N, Cirmi S, Mandalari G, Navarra M. In vitro effect of bergamot (Citrus bergamia) juice against cagA-positive and-negative clinical isolates of Helicobacter pylori. BMC Complement Altern Med., 2015, 15:256.
  40. Navarra M, Ferlazzo N, Cirmi S, Trapasso E, Bramanti P, Lombardo GE, Minciullo PL, Calapai G, Gangemi S. Effects of bergamot essential oil and its extractive fractions on SH-SY5Y human neuroblastoma cell growth. J Pharm Pharmacol., 2015, 67(8):1042-53.
  41. Giofrè SV, Romeo R, Carnovale C, Mancuso R, Cirmi S, Navarra M, Garozzo A, Chiacchio MA. Synthesis and biological properties of 5-(1H-1,2,3-triazol-4-yl)isoxazolidines: a new class of C-nucleosides. Molecules, 2015, 20(4):5260-75.
  42. Scala A, Piperno A, Risitano F, Cirmi S, Navarra M, Grassi G. Efficient synthesis of highly substituted tetrahydroindazolone derivatives. Mol Divers., 2015, 19(3):473-80.
  43. Risitano R, Currò M, Cirmi S, Ferlazzo N, Campiglia P, Caccamo D, Ientile R, Navarra M. Flavonoid fraction of Bergamot juice reduces LPS-induced inflammatory response through SIRT1-mediated NF-κB inhibition in THP-1 monocytes. PLoS One, 2014, 9(9):e107431.
  44. Visalli G, Ferlazzo N, Cirmi S, Campiglia P, Gangemi S, Pietro AD, Calapai G, Navarra M. Bergamot juice extract inhibits proliferation by inducing apoptosis in human colon cancer cells. Anticancer Agents Med Chem., 2014, 14, 1402-1413.
  45. Romeo R, Navarra M, Giofrè SV, Carnovale C, Cirmi S, Lanza G, Chiacchio MA. Synthesis and biological activity of new arenediyne-linked isoxazolidines. Bioorg Med Chem., 2014, 22(13):3379-85.
  46. Romeo R, Giofrè SV, Carnovale C, Chiacchio MA, Campisi A, Mancuso R, Cirmi S, Navarra M. Synthesis and Biological Activity of Triazole-Appended N,O-Nucleosides. European Journal of Organic Chemistry., 2014, 5442–544.

Azioni sul documento

pubblicato il 21/07/2017 — ultima modifica 09/05/2022