Selected Publications
Macrophage metabolism
- Menga A., Favia M., Spera I., Vegliante M.C., Gissi R., De Grassi A., Laera L., Campanella A., Gerbino A., Carrà G., Canton M., Loizzi V., Pierri C.L., Cormio G., Mazzone M. , Castegna A. N-acetylaspartate release by glutaminolytic ovarian cancer cells sustains protumoral macrophages (2021) EMBO Reports, 22 (9), art. no. e51981
- Canton M. #, Sánchez-Rodríguez R., Spera I., Venegas F.C., Favia M., Viola A., Castegna A. Reactive Oxygen Species in Macrophages: Sources and Targets (2021) Frontiers in Immunology, 12, art. no. 734229
- Menga A., Serra M., Todisco S., Riera-Domingo C., Ammarah U., Ehling M., Palmieri E.M., Di Noia M.A., Gissi R., Favia M., Pierri C.L., Porporato P.E., Castegna A.#, Mazzone M.# Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages (2020) EMBO Molecular Medicine, 12 (10), art. no. e11210
- Viola A., Munari F., Sánchez-Rodríguez R., Scolaro T., Castegna A.The metabolic signature of macrophage responses (2019) Frontiers in Immunology, 10, art. no. 1462
- Palmieri E.M., Menga A., Martín-Pérez R., Quinto A., Riera-Domingo C., De Tullio G., Hooper D.C., Lamers W.H., Ghesquière B., McVicar D.W., Guarini A., Mazzone M., Castegna A. Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis (2017) Cell Reports, 20 (7), pp. 1654 - 1666
- Sánchez-Rodríguez R., Tezze C., Agnellini A.H.R., Angioni R., Venegas F.C., Cioccarelli C., Munari F., Bertoldi N., Canton M., Desbats M.A., Salviati L., Gissi R., Castegna A., Soriano M.E., Sandri M., Scorrano L., Viola A., Molon B. OPA1 drives macrophage metabolism and functional commitment via p65 signaling (2023) Cell Death and Differentiation, 30 (3), pp. 742 - 752
- Sánchez-Rodríguez R., Munari F., Angioni R., Venegas F., Agnellini A., Castro-Gil M.P., Castegna A., Luisetto R., Viola A., Canton M. Targeting monoamine oxidase to dampen NLRP3 inflammasome activation in inflammation (2021) Cellular and Molecular Immunology, 18 (5), pp. 1311 - 1313
- Feno S., Munari F., Reane D.V., Gissi R., Hoang D.-H., Castegna A., Chazaud B., Viola A., Rizzuto R., Raffaello A. The dominant-negative mitochondrial calcium uniporter subunit MCUb drives macrophage polarization during skeletal muscle regeneration (2021) Science Signaling, 14 (707), art. no. eabf3838
- Palmieri E.M., Spera I., Menga A., Infantino V., Porcelli V., Iacobazzi V., Pierri C.L., Hooper D.C., Palmieri F., Castegna A. Acetylation of human mitochondrial citrate carrier modulates mitochondrial citrate/malate exchange activity to sustain NADPH production during macrophage activation (2015) Biochimica et Biophysica Acta - Bioenergetics, 1847 (8), pp. 729 - 738
Cancer metabolism
- Mazzone M. , Castegna A. A collaborative synthetase (2023) Nature Chemical Biology, 19 (3), pp. 255 – 256
- Masgras I., Cannino G., Ciscato F., Sanchez-Martin C., Darvishi F.B., Scantamburlo F., Pizzi M., Menga A., Fregona D., Castegna A., Rasola A. Tumor growth of neurofibromin-deficient cells is driven by decreased respiration and hampered by NAD+ and SIRT3 (2022) Cell Death and Differentiation, 29 (10), pp. 1996 - 2008
- Serra M., Di Matteo M., Serneels J., Pal R., Cafarello S.T., Lanza M., Sanchez-Martin C., Evert M., Castegna A., Calvisi D.F., Mazzone M., Columbano A. Deletion of Lactate Dehydrogenase-A Impairs Oncogene-Induced Mouse Hepatocellular Carcinoma Development (2022) Cellular and Molecular Gastroenterology and Hepatology, 14 (3), pp. 609 - 624
- Menga A., Palmieri E.M., Cianciulli A., Infantino V., Mazzone M., Scilimati A., Palmieri F., Castegna A.#, Iacobazzi V.# SLC25A26 overexpression impairs cell function via mtDNA hypermethylation and rewiring of methyl metabolism (2017) FEBS Journal, 284 (6), pp. 967 - 984
- Vozza A., Parisi G., De Leonardis F., Lasorsa F.M., Castegna A., Amorese D., Marmo R., Calcagnile V.M., Palmieri L., Ricquier D., Paradies E., Scarcia P., Palmieri F., Bouillaud F., Fiermonte G. UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation (2014) Proceedings of the National Academy of Sciences of the United States of America, 111 (3), pp. 960 - 965
ORCID: 0000-0003-0235-6847
The complete list of publication is available at:
https://www.scopus.com/authid/detail.uri?authorId=6602505420
https://scholar.google.com/citations?user=eGvuiR8AAAAJ&hl=en&oi=ao