Pubblicazioni
Publications
1: Capra R, Battaglia MA, Gaudioso A, Lopes L, Paolicelli D, Paoloni M, Pozzilli
C, Santilli V, Solaro C, Trojano M. The MoSt Project--More Steps in multiple
sclerosis: a Delphi method consensus initiative for the evaluation of mobility
management of MS patients in Italy. J Neurol. 2014 Jan 22.
2: Miller DH, Fazekas F, Montalban X, Reingold SC, Trojano M. Pregnancy, sex and
hormonal factors in multiple sclerosis. Mult Scler. 2014 Jan 20.
3: Giordano A, Lugaresi A, Confalonieri P, Granella F, Radice D, Trojano M,
Martinelli V, Solari A; on behalf of the SIMS-Practice groupa. Implementation of
the 'Sapere Migliora' information aid for newly diagnosed people with multiple
sclerosis in routine clinical practice: a late-phase controlled trial. Mult
Scler. 2014 Jan 13.
4: Portaccio E, Ghezzi A, Hakiki B, Sturchio A, Martinelli V, Moiola L, Patti F,
Mancardi GL, Solaro C, Tola MR, Pozzilli C, De Giglio L, Totaro R, Lugaresi A, De
Luca G, Paolicelli D, Marrosu MG, Comi G, Trojano M, Amato MP; for the MS Study
Group of the Italian Neurological Society. Postpartum relapses increase the risk
of disability progression in multiple sclerosis: the role of disease modifying
drugs. J Neurol Neurosurg Psychiatry. 2014 Jan 8.
5: Bassi M, Falautano M, Cilia S, Goretti B, Grobberio M, Pattini M, Pietrolongo
E, Viterbo RG, Amato MP, Benin M, Lugaresi A, Martinelli V, Montanari E, Patti F,
Trojano M, Delle Fave A. The coexistence of well- and ill-being in persons with
multiple sclerosis, their caregivers and health professionals. J Neurol Sci. 2014
Feb 15;337(1-2):67-73.
6: Pisani F, Sparaneo A, Tortorella C, Ruggieri M, Trojano M, Mola MG, Nicchia
GP, Frigeri A, Svelto M. Aquaporin-4 autoantibodies in Neuromyelitis Optica: AQP4
isoform-dependent sensitivity and specificity. PLoS One. 2013 Nov
15;8(11):e79185.
7: Kalincik T, Vivek V, Jokubaitis V, Lechner-Scott J, Trojano M, Izquierdo G,
Lugaresi A, Grand'maison F, Hupperts R, Oreja-Guevara C, Bergamaschi R, Iuliano
G, Alroughani R, Van Pesch V, Amato MP, Slee M, Verheul F, Fernandez-Bolanos R,
Fiol M, Spitaleri DL, Cristiano E, Gray O, Cabrera-Gomez JA, Shaygannejad V,
Herbert J, Vucic S, Needham M, Petkovska-Boskova T, Sirbu CA, Duquette P, Girard
M, Grammond P, Boz C, Giuliani G, Rio ME, Barnett M, Flechter S, Moore F, Singhal
B, Bacile EA, Saladino ML, Shaw C, Skromne E, Poehlau D, Vella N, Spelman T, Liew
D, Kilpatrick TJ, Butzkueven H; MSBase Study Group. Sex as a determinant of
relapse incidence and progressive course of multiple sclerosis. Brain. 2013
Dec;136(Pt 12):3609-17.
8: Patti F, Morra VB, Amato MP, Trojano M, Bastianello S, Tola MR, Cottone S,
Plant A, Picconi O; COGIMUS Study Group. Subcutaneous interferon β-1a may protect
against cognitive impairment in patients with relapsing-remitting multiple
sclerosis: 5-year follow-up of the COGIMUS study. PLoS One. 2013 Aug
30;8(8):e74111.
9: Tortorella C, Direnzo V, D'Onghia M, Trojano M. Brainstem PML lesion mimicking
MS plaque in a natalizumab-treated MS patient. Neurology. 2013 Oct
15;81(16):1470-1.
10: Hughes SE, Spelman T, Gray OM, Boz C, Trojano M, Lugaresi A, Izquierdo G,
Duquette P, Girard M, Grand'maison F, Grammond P, Oreja-Guevara C, Hupperts R,
Bergamaschi R, Giuliani G, Lechner-Scott J, Barnett M, Edite Rio M, Pesch VV,
Amato MP, Iuliano G, Slee M, Verheul F, Cristiano E, Fernández-Bolaños R, Poehlau
D, Saladino ML, Deri N, Cabrera-Gomez J, Vella N, Herbert J, Skromne E, Savino A,
Shaw C, Moore F, Vucic S, Petkovska-Boskova T, McDonnell G, Hawkins SA, Kee F,
Butzkueven H. Predictors and dynamics of postpartum relapses in women with
multiple sclerosis. Mult Scler. 2014 Jan 14.
11: Goretti B, Viterbo RG, Portaccio E, Niccolai C, Hakiki B, Piscolla E,
Iaffaldano P, Trojano M, Amato MP. Anxiety state affects information processing
speed in patients with multiple sclerosis. Neurol Sci. 2013 Sep 27.
12: Comi G, Battaglia MA, Bertolotto A, Del Sette M, Ghezzi A, Malferrari G,
Salvetti M, Sormani MP, Tesio L, Stolz E, Zaratin P, Mancardi G; CoSMo
Collaborative Study Group. Observational case-control study of the prevalence of
chronic cerebrospinal venous insufficiency in multiple sclerosis: results from
the CoSMo study. Mult Scler. 2013 Oct;19(11):1508-17.
13: Iaffaldano P, Ruggieri M, Viterbo RG, Mastrapasqua M, Trojano M. The
improvement of cognitive functions is associated with a decrease of plasma
Osteopontin levels in Natalizumab treated relapsing multiple sclerosis. Brain
Behav Immun. 2014 Jan;35:96-101.
14: Amato MP, Goretti B, Viterbo RG, Portaccio E, Niccolai C, Hakiki B,
Iaffaldano P, Trojano M. Computer-assisted rehabilitation of attention in
patients with multiple sclerosis: results of a randomized, double-blind trial.
Mult Scler. 2014 Jan;20(1):91-8.
15: Filippi M, Rocca MA, Bastianello S, Comi G, Gallo P, Gallucci M, Ghezzi A,
Marrosu MG, Minonzio G, Pantano P, Pozzilli C, Tedeschi G, Trojano M, Falini A,
De Stefano N. Guidelines from The Italian Neurological and Neuroradiological
Societies for the use of magnetic resonance imaging in daily life clinical
practice of multiple sclerosis patients. Neurol Sci. 2013 Dec;34(12):2085-93.
16: Kalincik T, Spelman T, Trojano M, Duquette P, Izquierdo G, Grammond P,
Lugaresi A, Hupperts R, Cristiano E, Van Pesch V, Grand'maison F, La Spitaleri D,
Rio ME, Flechter S, Oreja-Guevara C, Giuliani G, Savino A, Amato MP, Petersen T,
Fernandez-Bolanos R, Bergamaschi R, Iuliano G, Boz C, Lechner-Scott J, Deri N,
Gray O, Verheul F, Fiol M, Barnett M, van Munster E, Santiago V, Moore F, Slee M,
Saladino ML, Alroughani R, Shaw C, Kasa K, Petkovska-Boskova T, den
Braber-Moerland L, Chapman J, Skromne E, Herbert J, Poehlau D, Needham M, Bacile
EA, Arruda WO, Paine M, Singhal B, Vucic S, Cabrera-Gomez JA, Butzkueven H;
MSBase Study Group. Persistence on therapy and propensity matched outcome
comparison of two subcutaneous interferon beta 1a dosages for multiple sclerosis.
PLoS One. 2013 May 21;8(5):e63480.
17: Viterbo RG, Iaffaldano P, Trojano M. Verbal fluency deficits in clinically
isolated syndrome suggestive of multiple sclerosis. J Neurol Sci. 2013 Jul
15;330(1-2):56-60.
18: Pietrolongo E, Giordano A, Kleinefeld M, Confalonieri P, Lugaresi A,
Tortorella C, Pugliatti M, Radice D, Goss C, Heesen C, Solari A; AutoMS group.
Decision-making in multiple sclerosis consultations in Italy: third observer and
patient assessments. PLoS One. 2013;8(4):e60721.
19: Galeotti F, Massari M, D'Alessandro R, Beghi E, Chiò A, Logroscino G,
Filippini G, Benedetti MD, Pugliatti M, Santuccio C, Raschetti R; ITANG study
group. Risk of Guillain-Barré syndrome after 2010-2011 influenza vaccination. Eur
J Epidemiol. 2013 May;28(5):433-44.
20: Girolamo F, Lia A, Amati A, Strippoli M, Coppola C, Virgintino D, Roncali L,
Toscano A, Serlenga L, Trojano M. Overexpression of autophagic proteins in the
skeletal muscle of sporadic inclusion body myositis. Neuropathol Appl Neurobiol.
2013 Mar 4. doi: 10.1111/nan.12040.
21: Wolinsky JS, Narayana PA, Nelson F, Datta S, O'Connor P, Confavreux C, Comi
G, Kappos L, Olsson TP, Truffinet P, Wang L, Miller A, Freedman MS; Teriflunomide
Multiple Sclerosis Oral (TEMSO) Trial Group. Magnetic resonance imaging outcomes
from a phase III trial of teriflunomide. Mult Scler. 2013 Sep;19(10):1310-9.
22: Paolicelli D, D'Onghia M, Pellegrini F, Direnzo V, Iaffaldano P, Lavolpe V,
Trojano M. The impact of neutralizing antibodies on the risk of disease worsening
in interferon β-treated relapsing multiple sclerosis: a 5 year post-marketing
study. J Neurol. 2013 Jun;260(6):1562-8.
23: Ghezzi A, Pozzilli C, Grimaldi LM, Moiola L, Brescia-Morra V, Lugaresi A, Lus
G, Rinaldi F, Rocca MA, Trojano M, Bianchi A, Comi G, Filippi M; Italian MS Study
Group. Natalizumab in pediatric multiple sclerosis: results of a cohort of 55
cases. Mult Scler. 2013 Jul;19(8):1106-12.
24: Trojano M. Multiple sclerosis spasticity symptoms management. Endocannabinoid
system modulator data beyond clinical trials. Foreword. Expert Rev Neurother.
2013 Feb;13(3 Suppl 1):1.
25: Tortorella C, Romano R, Direnzo V, Taurisano P, Zoccolella S, Iaffaldano P,
Fazio L, Viterbo R, Popolizio T, Blasi G, Bertolino A, Trojano M. Load-dependent
dysfunction of the putamen during attentional processing in patients with
clinically isolated syndrome suggestive of multiple sclerosis. Mult Scler. 2013
Aug;19(9):1153-60.
26: Pugliatti M, Eskic D, Mikolcić T, Pitschnau-Michel D, Myhr KM, Sastre-Garriga
J, Otero S, Wieczynska L, Torje C, Holloway E, Rienhoff O, Friede T, Buckow K,
Ellenberger D, Hillert J, Glaser A, Flachenecker P, Fuge J, Schyns-Liharska T,
Kasilingam E, Moretti A, Thalheim C; EUReMS Consortium. Assess, compare and
enhance the status of Persons with Multiple Sclerosis (MS) in Europe: a European
Register for MS. Acta Neurol Scand Suppl. 2012;(195):24-30.
27: Pastò L, Portaccio E, Ghezzi A, Hakiki B, Giannini M, Razzolini L, Piscolla
E, De Giglio L, Pozzilli C, Paolicelli D, Trojano M, Marrosu MG, Patti F, La
Mantia L, Mancardi GL, Solaro C, Totaro R, Tola MR, Di Tommaso V, Lugaresi A,
Moiola L, Martinelli V, Comi G, Amato MP; MS Study Group of the Italian
Neurological Society. Epidural analgesia and cesarean delivery in multiple
sclerosis post-partum relapses: the Italian cohort study. BMC Neurol. 2012 Dec
31;12:165.
28: Messmer Uccelli M, Traversa S, Trojano M, Viterbo RG, Ghezzi A, Signori A.
Lack of information about multiple sclerosis in children can impact parents'
sense of competency and satisfaction within the couple. J Neurol Sci. 2013 Jan
15;324(1-2):100-5.
29: Trojano M, Lucchese G, Graziano G, Taylor BV, Simpson S Jr, Lepore V,
Grand'maison F, Duquette P, Izquierdo G, Grammond P, Amato MP, Bergamaschi R,
Giuliani G, Boz C, Hupperts R, Van Pesch V, Lechner-Scott J, Cristiano E, Fiol M,
Oreja-Guevara C, Saladino ML, Verheul F, Slee M, Paolicelli D, Tortorella C,
D'Onghia M, Iaffaldano P, Direnzo V, Butzkueven H; MSBase Study Group and the New
Zealand MS Prevalence Study Group. Geographical variations in sex ratio trends
over time in multiple sclerosis. PLoS One. 2012;7(10):e48078.
30: Giannini M, Portaccio E, Ghezzi A, Hakiki B, Pastò L, Razzolini L, Piscolla
E, De Giglio L, Pozzilli C, Paolicelli D, Trojano M, Marrosu MG, Patti F, La
Mantia L, Mancardi G, Solaro C, Totaro R, Tola MR, De Luca G, Lugaresi A, Moiola
L, Martinelli V, Comi G, Amato MP. Pregnancy and fetal outcomes after Glatiramer
Acetate exposure in patients with multiple sclerosis: a prospective observational
multicentric study. BMC Neurol. 2012 Oct 22;12:124.
31: Verheul F, Smolders J, Trojano M, Lepore V, Zwanikken C, Amato MP,
Grand'maison F, Butzkueven H, Marrosu M, Duquette P, Comi G, Izquierdo G,
Grammond P, Lus G, Petersen T, Bergamaschi R, Giuliani G, Boz C, Coniglio G, Van
Pesch V, Lechner-Scott J, Cavalla P, Granella F, Avolio C, Fiol M, Poehlau D,
Saladino ML, Gallo P, Deri N, Oleschko Arruda W, Paine M, Ferro M, Barnett M,
Cabrera-Gomez JA, Slee M, Moore F, Shaw C, Petkovska-Boskova T, Rutherford M,
Engelsen O, Damoiseaux J, Hupperts R. Fluctuations of MS births and UV-light
exposure. Acta Neurol Scand. 2013 May;127(5):301-8.
32: Zoccolella S, Tortorella C, Iaffaldano P, Direnzo V, D'Onghia M,
Luciannatelli E, Paolicelli D, Livrea P, Trojano M. Low serum urate levels are
associated to female gender in multiple sclerosis patients. PLoS One.
2012;7(7):e40608.
33: Meyniel C, Spelman T, Jokubaitis VG, Trojano M, Izquierdo G, Grand'Maison F,
Oreja-Guevara C, Boz C, Lugaresi A, Girard M, Grammond P, Iuliano G, Fiol M,
Cabrera-Gomez JA, Fernandez-Bolanos R, Giuliani G, Lechner-Scott J, Cristiano E,
Herbert J, Petkovska-Boskova T, Bergamaschi R, van Pesch V, Moore F, Vella N,
Slee M, Santiago V, Barnett M, Havrdova E, Young C, Sirbu CA, Tanner M,
Rutherford M, Butzkueven H; MSBasis Study Group. Country, sex, EDSS change and
therapy choice independently predict treatment discontinuation in multiple
sclerosis and clinically isolated syndrome. PLoS One. 2012;7(6):e38661.
34: Bergamaschi R, Quaglini S, Tavazzi E, Amato MP, Paolicelli D, Zipoli V,
Romani A, Tortorella C, Portaccio E, D'Onghia M, Garberi F, Bargiggia V, Trojano
M. Immunomodulatory therapies delay disease progression in multiple sclerosis.
Mult Scler. 2012 May 31.
35: Iaffaldano P, Viterbo RG, Paolicelli D, Lucchese G, Portaccio E, Goretti B,
Direnzo V, D'Onghia M, Zoccolella S, Amato MP, Trojano M. Impact of natalizumab
on cognitive performances and fatigue in relapsing multiple sclerosis: a
prospective, open-label, two years observational study. PLoS One.
2012;7(4):e35843.
36: de Tommaso M, Ceci E, Pica C, Trojano M, Delussi M, Franco G, Livrea P,
Ruggieri M. Serum levels of N-acetyl-aspartate in migraine and tension-type
headache. J Headache Pain. 2012 Jul;13(5):389-94.
37: Kister I, Chamot E, Cutter G, Bacon TE, Jokubaitis VG, Hughes SE, Gray OM,
Trojano M, Izquierdo G, Grand'Maison F, Duquette P, Lugaresi A, Grammond P, Boz
C, Hupperts R, Petersen T, Giuliani G, Oreja-Guevara C, Iuliano G, Lechner-Scott
J, Bergamaschi R, Rio ME, Verheul F, Fiol M, Van Pesch V, Slee M, Butzkueven H,
Herbert J; MSBase Investigators. Increasing age at disability milestones among MS
patients in the MSBase Registry. J Neurol Sci. 2012 Jul 15;318(1-2):94-9.
38: Ciccone MM, Galeandro AI, Scicchitano P, Zito A, Gesualdo M, Sassara M,
Cortese F, Dachille A, Carbonara R, Federico F, Livrea P, Trojano M. Multigate
quality Doppler profiles and morphological/hemodynamic alterations in multiple
sclerosis patients. Curr Neurovasc Res. 2012 May;9(2):120-7.
39: Cosentino M, Zaffaroni M, Trojano M, Giorelli M, Pica C, Rasini E, Bombelli
R, Ferrari M, Ghezzi A, Comi G, Livrea P, Lecchini S, Marino F. Dopaminergic
modulation of CD4+CD25(high) regulatory T lymphocytes in multiple sclerosis
patients during interferon-β therapy. Neuroimmunomodulation. 2012;19(5):283-92.
40: Zoccolella S, Tortorella C, Iaffaldano P, Direnzo V, D'Onghia M, Paolicelli
D, Livrea P, Trojano M. Elevated plasma homocysteine levels in patients with
multiple sclerosis are associated with male gender. J Neurol. 2012
Oct;259(10):2105-10.
41: Caragnano M, Tortorella P, Bergami A, Ruggieri M, Livrea P, Specchio LM,
Martino G, Trojano M, Furlan R, Avolio C. Monocytes P2X7 purinergic receptor is
modulated by glatiramer acetate in multiple sclerosis. J Neuroimmunol. 2012
Apr;245(1-2):93-7.
42: Hughes S, Spelman T, Trojano M, Lugaresi A, Izquierdo G, Grand'maison F,
Duquette P, Girard M, Grammond P, Oreja-Guevara C, Hupperts R, Boz C, Bergamaschi
R, Giuliani G, Rio ME, Lechner-Scott J, van Pesch V, Iuliano G, Fiol M, Verheul
F, Barnett M, Slee M, Herbert J, Kister I, Vella N, Moore F, Petkovska-Boskova T,
Shaygannejad V, Jokubaitis V, McDonnell G, Hawkins S, Kee F, Gray O, Butzkueven
H; MSBase Study Group. The Kurtzke EDSS rank stability increases 4 years after
the onset of multiple sclerosis: results from the MSBase Registry. J Neurol
Neurosurg Psychiatry. 2012 Mar;83(3):305-10.
43: Lechner-Scott J, Spencer B, de Malmanche T, Attia J, Fitzgerald M, Trojano M,
Grand'Maison F, Gomez JA, Izquierdo G, Duquette P, Girard M, Grammond P,
Oreja-Guevara C, Hupperts R, Bergamaschi R, Boz C, Giuliani G, van Pesch V,
Iuliano G, Fiol M, Cristiano E, Verheul F, Saladino ML, Slee M, Barnett M, Deri
N, Flechter S, Vella N, Shaw C, Herbert J, Moore F, Petkovska-Boskova T,
Jokubaitis V, Butzkueven H; MSBase study group. The frequency of CSF oligoclonal
banding in multiple sclerosis increases with latitude. Mult Scler. 2012
Jul;18(7):974-82.
44: Iaffaldano P, Lucchese G, Trojano M. Treating multiple sclerosis with
natalizumab. Expert Rev Neurother. 2011 Dec;11(12):1683-92.
45: Martinelli V, Cocco E, Capra R, Salemi G, Gallo P, Capobianco M, Pesci I,
Ghezzi A, Pozzilli C, Lugaresi A, Bellantonio P, Amato MP, Grimaldi LM, Trojano
M, Mancardi GL, Bergamaschi R, Gasperini C, Rodegher M, Straffi L, Ponzio M, Comi
G; Italian Mitoxantrone Group. Acute myeloid leukemia in Italian patients with
multiple sclerosis treated with mitoxantrone. Neurology. 2011 Nov
22;77(21):1887-95.
46: Ruggieri M, Serpino C, Ceci E, Sciruicchio V, Franco G, Pica C, Trojano M,
Livrea P, de Tommaso M. Serum levels of N-acetylaspartate in Huntington's
disease: preliminary results. Mov Disord. 2012 Feb;27(2):329-30.
47: Bastianello S, Giugni E, Amato MP, Tola MR, Trojano M, Galletti S,
Luccichenti G, Quarantelli M, Picconi O, Patti F; COGIMUS study group. Changes in
magnetic resonance imaging disease measures over 3 years in mildly disabled
patients with relapsing-remitting multiple sclerosis receiving interferon β-1a in
the COGnitive Impairment in MUltiple Sclerosis (COGIMUS) study. BMC Neurol. 2011
Oct 14;11:125.
48: O'Connor P, Wolinsky JS, Confavreux C, Comi G, Kappos L, Olsson TP,
Benzerdjeb H, Truffinet P, Wang L, Miller A, Freedman MS; TEMSO Trial Group.
Randomized trial of oral teriflunomide for relapsing multiple sclerosis. N Engl J
Med. 2011 Oct 6;365(14):1293-303.
49: Patti F, Amato MP, Trojano M, Bastianello S, Tola MR, Picconi O, Cilia S,
Cottone S, Grimaldi LM; COGIMUS study group. Longitudinal changes in social
functioning in mildly disabled patients with relapsing-remitting multiple
sclerosis receiving subcutaneous interferon β-1a: results from the COGIMUS
(COGnitive Impairment in MUltiple Sclerosis) study (II). Qual Life Res. 2012
Sep;21(7):1111-21.
50: Goretti B, Portaccio E, Ghezzi A, Lori S, Moiola L, Falautano M, Viterbo R,
Patti F, Vecchio R, Pozzilli C, Bianchi V, Cappiello S, Comi G, Trojano M, Amato
MP; Multiple Sclerosis Study Group of the Italian Neurological Society. Fatigue
and its relationships with cognitive functioning and depression in paediatric
multiple sclerosis. Mult Scler. 2012 Mar;18(3):329-34.
51: Portaccio E, Ghezzi A, Hakiki B, Martinelli V, Moiola L, Patti F, La Mantia
L, Mancardi GL, Solaro C, Tola MR, Pozzilli C, De Giglio L, Totaro R, Lugaresi A,
De Luca G, Paolicelli D, Marrosu MG, Comi G, Trojano M, Amato MP; MS Study Group
of the Italian Neurological Society. Breastfeeding is not related to postpartum
relapses in multiple sclerosis. Neurology. 2011 Jul 12;77(2):145-50.
52: Girolamo F, Ferrara G, Strippoli M, Rizzi M, Errede M, Trojano M, Perris R,
Roncali L, Svelto M, Mennini T, Virgintino D. Cerebral cortex demyelination and
oligodendrocyte precursor response to experimental autoimmune encephalomyelitis.
Neurobiol Dis. 2011 Sep;43(3):678-89.
53: Martino D, Chiarotti F, Buttiglione M, Cardona F, Creti R, Nardocci N,
Orefici G, Veneselli E, Rizzo R; Italian Tourette Syndrome Study Group. The
relationship between group A streptococcal infections and Tourette syndrome: a
study on a large service-based cohort. Dev Med Child Neurol. 2011
Oct;53(10):951-7.
54: Tortorella C, Ruggieri M, Di Monte E, Ceci E, Iaffaldano P, Direnzo V,
Mastrapasqua M, Frigeri A, Amato MP, Hakiki B, Ghezzi A, Lugaresi A, De Luca G,
Patti F, D'Amico E, Sola P, Simone AM, Svelto M, Livrea P, Trojano M. Serum and
CSF N-acetyl aspartate levels differ in multiple sclerosis and neuromyelitis
optica. J Neurol Neurosurg Psychiatry. 2011 Dec;82(12):1355-9.
55: Giordano A, Granella F, Lugaresi A, Martinelli V, Trojano M, Confalonieri P,
Radice D, Solari A; SIMS-Trial group. Anxiety and depression in multiple
sclerosis patients around diagnosis. J Neurol Sci. 2011 Aug 15;307(1-2):86-91.
56: Khatri B, Barkhof F, Comi G, Hartung HP, Kappos L, Montalban X, Pelletier J,
Stites T, Wu S, Holdbrook F, Zhang-Auberson L, Francis G, Cohen JA; TRANSFORMS
Study Group. Comparison of fingolimod with interferon beta-1a in
relapsing-remitting multiple sclerosis: a randomised extension of the TRANSFORMS
study. Lancet Neurol. 2011 Jun;10(6):520-9.
57: Trojano M. Multiple sclerosis: the evolving diagnostic criteria for multiple
sclerosis. Nat Rev Neurol. 2011 May;7(5):251-2.
58: Patti F, Amato MP, Trojano M, Bastianello S, Tola MR, Picconi O, Cilia S,
Cottone S, Centonze D, Gasperini C; COGIMUS Study Group. Quality of life,
depression and fatigue in mildly disabled patients with relapsing-remitting
multiple sclerosis receiving subcutaneous interferon beta-1a: 3-year results from
the COGIMUS (COGnitive Impairment in MUltiple Sclerosis) study. Mult Scler. 2011
Aug;17(8):991-1001.
59: Trojano M, Paolicelli D, Tortorella C, Iaffaldano P, Lucchese G, Di Renzo V,
D'Onghia M. Natural history of multiple sclerosis: have available therapies
impacted long-term prognosis? Neurol Clin. 2011 May;29(2):309-21.
60: Edan G, Comi G, Le Page E, Leray E, Rocca MA, Filippi M; French–Italian
Mitoxantrone Interferon-beta-1b Trial Group. Mitoxantrone prior to interferon
beta-1b in aggressive relapsing multiple sclerosis: a 3-year randomised trial. J
Neurol Neurosurg Psychiatry. 2011 Dec;82(12):1344-50.
61: Ruggieri M, Tortorella C, Ceci E, Paolicelli D, Solfrizzi V, Di Bitonto G,
Pica C, Mastrapasqua M, Livrea P, Trojano M. Age-related changes of serum
N-acetyl-aspartate in healthy controls. Age Ageing. 2011 May;40(3):391-5.
62: Patti F, Amato MP, Trojano M, Solaro C, Pappalardo A, Zipoli V, Portaccio E,
Paolicelli D, Paolillo A, Mennini FS, Marcellusi A, Ricci C, Battaglia MA.
Multiple sclerosis in Italy: cost-of-illness study. Neurol Sci. 2011
Oct;32(5):787-94.
63: Ghezzi A, Grimaldi LM, Marrosu MG, Pozzilli C, Comi G, Bertolotto A, Trojano
M, Gallo P, Capra R, Centonze D, Millefiorini E, Sotgiu S, Brescia Morra V, Amato
MP, Lugaresi A, Mancardi G, Caputo D, Montanari E, Provinciali L, Durelli L,
Bergamaschi R, Bellantonio P, Tola MR, Cottone S, Savettieri G, Tedeschi G;
MS-SIN Study Group. Natalizumab therapy of multiple sclerosis: recommendations of
the Multiple Sclerosis Study Group--Italian Neurological Society. Neurol Sci.
2011 Apr;32(2):351-8.
64: Pisani F, Mastrototaro M, Rossi A, Nicchia GP, Tortorella C, Ruggieri M,
Trojano M, Frigeri A, Svelto M. Identification of two major conformational
aquaporin-4 epitopes for neuromyelitis optica autoantibody binding. J Biol Chem.
2011 Mar 18;286(11):9216-24.
65: Amato MP, Portaccio E, Ghezzi A, Hakiki B, Zipoli V, Martinelli V, Moiola L,
Patti F, La Mantia L, Mancardi GL, Solaro C, Tola MR, Pozzilli C, De Giglio L,
Totaro R, Lugaresi A, Di Tommaso V, Paolicelli D, Marrosu MG, Comi G, Pellegrini
F, Trojano M; MS Study Group of the Italian Neurological Society. Pregnancy and
fetal outcomes after interferon-β exposure in multiple sclerosis. Neurology. 2010
Nov 16;75(20):1794-802.
66: Amato MP, Goretti B, Ghezzi A, Lori S, Zipoli V, Moiola L, Falautano M, De
Caro MF, Viterbo R, Patti F, Vecchio R, Pozzilli C, Bianchi V, Roscio M,
Martinelli V, Comi G, Portaccio E, Trojano M; Multiple Sclerosis Study Group of
the Italian Neurological Society. Cognitive and psychosocial features in
childhood and juvenile MS: two-year follow-up. Neurology. 2010 Sep
28;75(13):1134-40.
67: Solari A, Martinelli V, Trojano M, Lugaresi A, Granella F, Giordano A,
Messmer Uccelli M, D'Alessandro R, Pucci E, Confalonieri P, Borreani C;
SIMS-Trial group. An information aid for newly diagnosed multiple sclerosis
patients improves disease knowledge and satisfaction with care. Mult Scler. 2010
Nov;16(11):1393-405.
68: Solari A, Mattarozzi K, Vignatelli L, Giordano A, Russo PM, Uccelli MM,
D'Alessandro R; SIMS-Trial group; GERONIMUS group. Development and validation of
a patient self-assessed questionnaire on satisfaction with communication of the
multiple sclerosis diagnosis. Mult Scler. 2010 Oct;16(10):1237-47.
69: Trojano M. Improving combination trials for multiple sclerosis. Lancet
Neurol. 2010 Jul;9(7):646-7.
70: Goretti B, Ghezzi A, Portaccio E, Lori S, Zipoli V, Razzolini L, Moiola L,
Falautano M, De Caro MF, Viterbo R, Patti F, Vecchio R, Pozzilli C, Bianchi V,
Roscio M, Comi G, Trojano M, Amato MP; Study Group of the Italian Neurological
Society. Psychosocial issue in children and adolescents with multiple sclerosis.
Neurol Sci. 2010 Aug;31(4):467-70.
71: Radue EW, Stuart WH, Calabresi PA, Confavreux C, Galetta SL, Rudick RA,
Lublin FD, Weinstock-Guttman B, Wynn DR, Fisher E, Papadopoulou A, Lynn F,
Panzara MA, Sandrock AW; SENTINEL Investigators. Natalizumab plus interferon
beta-1a reduces lesion formation in relapsing multiple sclerosis. J Neurol Sci.
2010 May 15;292(1-2):28-35.
72: Giovannoni G, Comi G, Cook S, Rammohan K, Rieckmann P, Soelberg Sørensen P,
Vermersch P, Chang P, Hamlett A, Musch B, Greenberg SJ; CLARITY Study Group. A
placebo-controlled trial of oral cladribine for relapsing multiple sclerosis. N
Engl J Med. 2010 Feb 4;362(5):416-26.
73: Cohen JA, Barkhof F, Comi G, Hartung HP, Khatri BO, Montalban X, Pelletier J,
Capra R, Gallo P, Izquierdo G, Tiel-Wilck K, de Vera A, Jin J, Stites T, Wu S,
Aradhye S, Kappos L; TRANSFORMS Study Group. Oral fingolimod or intramuscular
interferon for relapsing multiple sclerosis. N Engl J Med. 2010 Feb
4;362(5):402-15.
74: Patti F, Amato MP, Bastianello S, Caniatti L, Di Monte E, Ferrazza P, Goretti
B, Gallo P, Morra VB, Lo Fermo S, Picconi O, Tola MR, Trojano M; COGIMUS Study
Group. Effects of immunomodulatory treatment with subcutaneous interferon beta-1a
on cognitive decline in mildly disabled patients with relapsing-remitting
multiple sclerosis. Mult Scler. 2010 Jan;16(1):68-77.
75: Giordano A, Uccelli MM, Pucci E, Martinelli V, Borreani C, Lugaresi A,
Trojano M, Granella F, Confalonieri P, Radice D, Solari A; SIMS-Trial group. The
Multiple Sclerosis Knowledge Questionnaire: a self-administered instrument for
recently diagnosed patients. Mult Scler. 2010 Jan;16(1):100-11.
76: Iaffaldano P, D'Onghia M, Trojano M. Safety profile of Tysabri: international
risk management plan. Neurol Sci. 2009 Oct;30 Suppl 2:S159-62.
77: Trojano M, Pellegrini F, Paolicelli D, Fuiani A, Di Renzo V. observational
studies: propensity score analysis of non-randomized data. Int MS J. 2009
Sep;16(3):90-7.
78: Petzold A, Altintas A, Andreoni L, Bartos A, Berthele A, Blankenstein MA,
Buee L, Castellazzi M, Cepok S, Comabella M, Constantinescu CS, Deisenhammer F,
Deniz G, Erten G, Espiño M, Fainardi E, Franciotta D, Freedman MS, Giedraitis V,
Gilhus NE, Giovannoni G, Glabinski A, Grieb P, Hartung HP, Hemmer B, Herukka SK,
Hintzen R, Ingelsson M, Jackson S, Jacobsen S, Jafari N, Jalosinski M, Jarius S,
Kapaki E, Kieseier BC, Koel-Simmelink MJ, Kornhuber J, Kuhle J, Kurzepa J, Lalive
PH, Lannfelt L, Lehmensiek V, Lewczuk P, Livrea P, Marnetto F, Martino D, Menge
T, Norgren N, Papuć E, Paraskevas GP, Pirttilä T, Rajda C, Rejdak K, Ricny J,
Ripova D, Rosengren L, Ruggieri M, Schraen S, Shaw G, Sindic C, Siva A, Stigbrand
T, Stonebridge I, Topcular B, Trojano M, Tumani H, Twaalfhoven HA, Vécsei L, Van
Pesch V, Vanderstichele H, Vedeler C, Verbeek MM, Villar LM, Weissert R,
Wildemann B, Yang C, Yao K, Teunissen CE. Neurofilament ELISA validation. J
Immunol Methods. 2010 Jan 31;352(1-2):23-31.
79: Trojano M, Pellegrini F, Paolicelli D, Fuiani A, Zimatore GB, Tortorella C,
Simone IL, Patti F, Ghezzi A, Zipoli V, Rossi P, Pozzilli C, Salemi G, Lugaresi
A, Bergamaschi R, Millefiorini E, Clerico M, Lus G, Vianello M, Avolio C, Cavalla
P, Lepore V, Livrea P, Comi G, Amato MP; Italian Multiple Sclerosis Database
Network (MSDN) Group. Real-life impact of early interferon beta therapy in
relapsing multiple sclerosis. Ann Neurol. 2009 Oct;66(4):513-20.
80: Vukusic S, Ionescu I, El-Etr M, Schumacher M, Baulieu EE, Cornu C, Confavreux
C; Prevention of Post-Partum Relapses with Progestin and Estradiol in Multiple
Sclerosis Study Group. The Prevention of Post-Partum Relapses with Progestin and
Estradiol in Multiple Sclerosis (POPART'MUS) trial: rationale, objectives and
state of advancement. J Neurol Sci. 2009 Nov 15;286(1-2):114-8.
81: O'Connor P, Filippi M, Arnason B, Comi G, Cook S, Goodin D, Hartung HP,
Jeffery D, Kappos L, Boateng F, Filippov V, Groth M, Knappertz V, Kraus C,
Sandbrink R, Pohl C, Bogumil T; BEYOND Study Group, O'Connor P, Filippi M,
Arnason B, Cook S, Goodin D, Hartung HP, Kappos L, Jeffery D, Comi G. 250 microg
or 500 microg interferon beta-1b versus 20 mg glatiramer acetate in
relapsing-remitting multiple sclerosis: a prospective, randomised, multicentre
study. Lancet Neurol. 2009 Oct;8(10):889-97. doi: 10.1016/S1474-4422(09)70226-1.
Epub 2009 Sep 2. Erratum in: Lancet Neurol. 2011 Feb;10(2):115. Lancet Neurol.
2009 Nov;8(11):981. Lancet Neurol. 2012 Jan;11(1):27.
82: Paolicelli D, Direnzo V, Trojano M. Review of interferon beta-1b in the
treatment of early and relapsing multiple sclerosis. Biologics. 2009;3:369-76.
83: Trojano M, Pellegrini F, Paolicelli D, Fuiani A, Zimatore GB, Tortorella C,
Simone IL, Patti F, Ghezzi A, Portaccio E, Rossi P, Pozzilli C, Salemi G,
Lugaresi A, Bergamaschi R, Millefiorini E, Clerico M, Lus G, Vianello M, Avolio
C, Cavalla P, Iaffaldano P, Direnzo V, D'Onghia M, Lepore V, Livrea P, Comi G,
Amato MP; Italian Multiple Sclerosis Database Network Group. Post-marketing of
disease modifying drugs in multiple sclerosis: an exploratory analysis of gender
effect in interferon beta treatment. J Neurol Sci. 2009 Nov 15;286(1-2):109-13.
84: Patti F, Amato MP, Trojano M, Bastianello S, Tola MR, Goretti B, Caniatti L,
Di Monte E, Ferrazza P, Brescia Morra V, Lo Fermo S, Picconi O, Luccichenti G;
COGIMUS Study Group. Cognitive impairment and its relation with disease measures
in mildly disabled patients with relapsing-remitting multiple sclerosis: baseline
results from the Cognitive Impairment in Multiple Sclerosis (COGIMUS) study. Mult
Scler. 2009 Jul;15(7):779-88.
85: Ghezzi A, Amato MP, Annovazzi P, Capobianco M, Gallo P, La Mantia L, Marrosu
MG, Martinelli V, Milani N, Moiola L, Patti F, Pozzilli C, Trojano M, Zaffaroni
M, Comi G; ITEMS (Immunomodulatory Treatment of Early-onset MS) Group. Long-term
results of immunomodulatory treatment in children and adolescents with multiple
sclerosis: the Italian experience. Neurol Sci. 2009 Jun;30(3):193-9.
86: Trojano M, Avolio C. Epstein-Barr virus (EBV) and multiple sclerosis
association: EBV has a primary or secondary role? J Neurol Neurosurg Psychiatry.
2009 May;80(5):469.
87: Hussain H, Usman A, Raza Q, Amato MP, Goretti B, Ghezzi A, Lori S, Zipoli V,
Portaccio E, Moiola L, Falautano M, De Caro MF, Lopez M, Patti F, Vecchio R,
Pozzilli C, Bianchi V, Roscio M, Comi G, Trojano M. Cognitive and psychosocial
features of childhood and juvenile MS. Neurology. 2009 Mar 31;72(13):1189; author
reply1189-90.
88: Portaccio E, Goretti B, Lori S, Zipoli V, Centorrino S, Ghezzi A, Patti F,
Bianchi V, Comi G, Trojano M, Amato MP; Multiple Sclerosis Study Group of the
Italian Neurological Society. The brief neuropsychological battery for children:
a screening tool for cognitive impairment in childhood and juvenile multiple
sclerosis. Mult Scler. 2009 May;15(5):620-6.
89: Patti F, Amato MP, Bastianello S, Caniatti L, Di Monte E, Lijoi F, Goretti B,
Messina S, Picconi O, Tola MR, Trojano M. Subcutaneous Interferon Beta-1a Has a
Positive Effect on Cognitive Performance in Mildly Disabled Patients with
Relapsing-Remitting Multiple Sclerosis: 2-Year Results from the COGIMUS Study.
Ther Adv Neurol Disord. 2009 Mar;2(2):67-77.
90: Nicchia GP, Mastrototaro M, Rossi A, Pisani F, Tortorella C, Ruggieri M, Lia
A, Trojano M, Frigeri A, Svelto M. Aquaporin-4 orthogonal arrays of particles are
the target for neuromyelitis optica autoantibodies. Glia. 2009
Oct;57(13):1363-73.
91: Bellomi F, Bramanti P, Trojano M, Scagnolari C, Muto A, Sessa E, La Volpe V,
Russo P, Antonelli G. Neutralizing and binding antibodies to interferon beta in
patients with multiple sclerosis: a comparison of assay results from three
italian centres. J Immunoassay Immunochem. 2009;30(1):40-50.
92: Trojano M, Paolicelli D, Fuiani A, Pellegrini F, Iaffaldano P, Direnzo V,
D'Onghia M. Postmarketing evidence of disease-modifying drugs in multiple
sclerosis. Neurol Sci. 2008 Sep;29 Suppl 2:S225-6.
93: Mikol DD, Barkhof F, Chang P, Coyle PK, Jeffery DR, Schwid SR, Stubinski B,
Uitdehaag B; REGARD study group. Comparison of subcutaneous interferon beta-1a
with glatiramer acetate in patients with relapsing multiple sclerosis (the REbif
vs Glatiramer Acetate in Relapsing MS Disease [REGARD] study): a multicentre,
randomised, parallel, open-label trial. Lancet Neurol. 2008 Oct;7(10):903-14.
94: Cocco E, Sardu C, Gallo P, Capra R, Amato MP, Trojano M, Uccelli A, Marrosu
MG; FEMIMS Group. Frequency and risk factors of mitoxantrone-induced amenorrhea
in multiple sclerosis: the FEMIMS study. Mult Scler. 2008 Nov;14(9):1225-33.
95: Italian REMS Study Group, Manconi M, Ferini-Strambi L, Filippi M, Bonanni E,
Iudice A, Murri L, Gigli GL, Fratticci L, Merlino G, Terzano G, Granella F,
Parrino L, Silvestri R, Aricò I, Dattola V, Russo G, Luongo C, Cicolin A, Tribolo
A, Cavalla P, Savarese M, Trojano M, Ottaviano S, Cirignotta F, Simioni V, Salvi
F, Mondino F, Perla F, Chinaglia G, Zuliani C, Cesnik E, Granieri E, Placidi F,
Palmieri MG, Manni R, Terzaghi M, Bergamaschi R, Rocchi R, Ulivelli M, Bartalini
S, Ferri R, Lo Fermo S, Ubiali E, Viscardi M, Rottoli M, Nobili L, Protti A,
Ferrillo F, Allena M, Mancardi G, Guarnieri B, Londrillo F. Multicenter
case-control study on restless legs syndrome in multiple sclerosis: the REMS
study. Sleep. 2008 Jul;31(7):944-52.
96: Ruggieri M, Pica C, Lia A, Zimatore GB, Modesto M, Di Liddo E, Specchio LM,
Livrea P, Trojano M, Avolio C. Combination treatment of Glatiramer Acetate and
Minocycline affects phenotype expression of blood monocyte-derived dendritic
cells in Multiple Sclerosis patients. J Neuroimmunol. 2008 Jul 15;197(2):140-6.
97: Ramunni A, De Robertis F, Brescia P, Saliani MT, Amoruso M, Prontera M,
Dimonte E, Trojano M, Coratelli P. A case report of double filtration
plasmapheresis in an acute episode of multiple sclerosis. Ther Apher Dial. 2008
Jun;12(3):250-4.
98: Cappellano G, Orilieri E, Comi C, Chiocchetti A, Bocca S, Boggio E,
Bernardone IS, Cometa A, Clementi R, Barizzone N, D'Alfonso S, Corrado L,
Galimberti D, Scarpini E, Guerini FR, Caputo D, Paolicelli D, Trojano M,
Figà-Talamanca L, Salvetti M, Perla F, Leone M, Monaco F, Dianzani U. Variations
of the perforin gene in patients with multiple sclerosis. Genes Immun. 2008
Jul;9(5):438-44.
99: Amato MP, Goretti B, Ghezzi A, Lori S, Zipoli V, Portaccio E, Moiola L,
Falautano M, De Caro MF, Lopez M, Patti F, Vecchio R, Pozzilli C, Bianchi V,
Roscio M, Comi G, Trojano M; Multiple Sclerosis Study Group of the Italian
Neurological Society. Cognitive and psychosocial features of childhood and
juvenile MS. Neurology. 2008 May 13;70(20):1891-7.
100: D'Alfonso S, Bolognesi E, Guerini FR, Barizzone N, Bocca S, Ferrante D,
Castelli L, Bergamaschi L, Agliardi C, Ferrante P, Naldi P, Leone M, Caputo D,
Ballerini C, Salvetti M, Galimberti D, Massacesi L, Trojano M,
Momigliano-Richiardi P. A sequence variation in the MOG gene is involved in
multiple sclerosis susceptibility in Italy. Genes Immun. 2008 Jan;9(1):7-15.
101: Trojano M. Is it time to use observational data to estimate treatment
effectiveness in multiple sclerosis? Neurology. 2007 Oct 9;69(15):1478-9.
102: Ruggieri M, Avolio C, Livrea P, Trojano M. Glatiramer acetate in multiple
sclerosis: a review. CNS Drug Rev. 2007 Summer;13(2):178-91. Review.
103: Solari A, Acquarone N, Pucci E, Martinelli V, Marrosu MG, Trojano M,
Borreani C, Messmer Uccelli M. Communicating the diagnosis of multiple sclerosis
- a qualitative study. Mult Scler. 2007 Jul;13(6):763-9.
104: Ghezzi A, Amato MP, Capobianco M, Gallo P, Marrosu MG, Martinelli V,
Milanese C, Moiola L, Milani N, La Mantia L, Patti F, Pozzilli C, Trojano M, Comi
G, Zaffaroni M; Immunomodulatory Treatment of Early-onset MS (ITEMS) Group.
Treatment of early-onset multiple sclerosis with intramuscular interferonbeta-1a:
long-term results. Neurol Sci. 2007 Jun;28(3):127-32.
105: Trojano M, Pellegrini F, Fuiani A, Paolicelli D, Zipoli V, Zimatore GB, Di
Monte E, Portaccio E, Lepore V, Livrea P, Amato MP. New natural history of
interferon-beta-treated relapsing multiple sclerosis. Ann Neurol. 2007
Apr;61(4):300-6.
106: Patti F, Amato MP, Battaglia MA, Pitaro M, Russo P, Solaro C, Trojano M.
Caregiver quality of life in multiple sclerosis: a multicentre Italian study.
Mult Scler. 2007 Apr;13(3):412-9.
107: Scagnolari C, Duda P, Bagnato F, De Vito G, Alberelli A, Lavolpe V, Girardi
E, Durastanti V, Trojano M, Kappos L, Antonelli G. Pharmacodynamics of interferon
beta in multiple sclerosis patients with or without serum neutralizing
antibodies. J Neurol. 2007 May;254(5):597-604.
108: Giorelli M, Livrea P, Minervini MG, Trojano M. Immunomodulatory properties
of increased levels of liver X receptor beta in peripheral blood mononuclear
cells from multiple sclerosis patients. Exp Neurol. 2007 Apr;204(2):759-66.
109: Amato MP, Portaccio E, Goretti B, Zipoli V, Ricchiuti L, De Caro MF, Patti
F, Vecchio R, Sorbi S, Trojano M. The Rao's Brief Repeatable Battery and Stroop
Test: normative values with age, education and gender corrections in an Italian
population. Mult Scler. 2006 Dec;12(6):787-93.
110: Butzkueven H, Chapman J, Cristiano E, Grand'Maison F, Hoffmann M, Izquierdo
G, Jolley D, Kappos L, Leist T, Pöhlau D, Rivera V, Trojano M, Verheul F,
Malkowski JP. MSBase: an international, online registry and platform for
collaborative outcomes research in multiple sclerosis. Mult Scler. 2006
Dec;12(6):769-74.
111: Bergamaschi R, Quaglini S, Trojano M, Amato MP, Tavazzi E, Paolicelli D,
Zipoli V, Romani A, Fuiani A, Portaccio E, Berzuini C, Montomoli C, Bastianello
S, Cosi V. Early prediction of the long term evolution of multiple sclerosis: the
Bayesian Risk Estimate for Multiple Sclerosis (BREMS) score. J Neurol Neurosurg
Psychiatry. 2007 Jul;78(7):757-9.
112: Trojano M, Russo P, Fuiani A, Paolicelli D, Di Monte E, Granieri E, Rosati
G, Savettieri G, Comi G, Livrea P; MSDN Study Group. The Italian Multiple
Sclerosis Database Network (MSDN): the risk of worsening according to IFNbeta
exposure in multiple sclerosis. Mult Scler. 2006 Oct;12(5):578-85.
113: Trojano M, Paolicelli D, Lepore V, Fuiani A, Di Monte E, Pellegrini F, Russo
P, Livrea P, Comi G; Italian MSDN Group. Italian Multiple Sclerosis Database
Network. Neurol Sci. 2006 Sep;27 Suppl 5:S358-61.
114: Games Collaborative Group, Ban M, Booth D, Heard R, Stewart G, Goris A,
Vandenbroeck K, Dubois B, Laaksonen M, Ilonen J, Alizadeh M, Edan G, Babron MC,
Brassat D, Clanet M, Cournu-Rebeix I, Fontaine B, Semana G, Goedde R, Epplen J,
Weber A, Infante-Duarte C, Zipp F, Rajda C, Bencsik K, Vécsei L, Heggarty S,
Graham C, Hawkins S, Liguori M, Momigliano-Richiardi P, Caputo D, Grimaldi LM,
Leone M, Massacesi L, Milanese C, Salvetti M, Savettieri G, Trojano M, Bielecki
B, Mycko MP, Selmaj K, Santos M, Maciel P, Pereira C, Silva A, Silva BM, Coraddu
F, Marrosu MG, Akesson E, Hillert J, Datta P, Oturai A, Harbo HF, Spurkland A,
Goertsches R, Villoslada P, Eraksoy M, Hensiek A, Compston A, Setakis E, Gray J,
Yeo TW, Sawcer S. Linkage disequilibrium screening for multiple sclerosis
implicates JAG1 and POU2AF1 as susceptibility genes in Europeans. J Neuroimmunol.
2006 Oct;179(1-2):108-16.
115: Amato MP, Zipoli V, Goretti B, Portaccio E, De Caro MF, Ricchiuti L,
Siracusa G, Masini M, Sorbi S, Trojano M. Benign multiple sclerosis: cognitive,
psychological and social aspects in a clinical cohort. J Neurol. 2006
Aug;253(8):1054-9.
116: Nocentini U, Pasqualetti P, Bonavita S, Buccafusca M, De Caro MF, Farina D,
Girlanda P, Le Pira F, Lugaresi A, Quattrone A, Reggio A, Salemi G, Savettieri G,
Tedeschi G, Trojano M, Valentino P, Caltagirone C. Cognitive dysfunction in
patients with relapsing-remitting multiple sclerosis. Mult Scler. 2006
Feb;12(1):77-87.
117: Trojano M, Paolicelli D, Zimatore GB, De Robertis F, Fuiani A, Di Monte E,
Livrea P. The IFNbeta treatment of multiple sclerosis (MS) in clinical practice:
the experience at the MS Center of Bari, Italy. Neurol Sci. 2005 Dec;26 Suppl
4:S179-82.
118: Tortorella C, Bellacosa A, Paolicelli D, Fuiani A, Di Monte E, Simone IL,
Giaquinto P, Livrea P, Trojano M. Age-related gadolinium-enhancement of MRI brain
lesions in multiple sclerosis. J Neurol Sci. 2005 Dec 15;239(1):95-9.
119: Ruggieri M, Avolio C, Scacco S, Pica C, Lia A, Zimatore GB, Papa S, Livrea
P, Trojano M. Glatiramer acetate induces pro-apoptotic mechanisms involving
Bcl-2, Bax and Cyt-c in peripheral lymphocytes from multiple sclerosis patients.
J Neurol. 2006 Feb;253(2):231-6.
120: Avolio C, Filippi M, Tortorella C, Rocca MA, Ruggieri M, Agosta F, Tomassini
V, Pozzilli C, Stecchi S, Giaquinto P, Livrea P, Trojano M. Serum MMP-9/TIMP-1
and MMP-2/TIMP-2 ratios in multiple sclerosis: relationships with different
magnetic resonance imaging measures of disease activity during IFN-beta-1a
treatment. Mult Scler. 2005 Aug;11(4):441-6.
121: Ghezzi A, Amato MP, Capobianco M, Gallo P, Marrosu G, Martinelli V, Milani
N, Milanese C, Moiola L, Patti F, Pilato V, Pozzilli C, Trojano M, Zaffaroni M,
Comi G; Immunomodulatory Treatment of Early onset MS Group. Disease-modifying
drugs in childhood-juvenile multiple sclerosis: results of an Italian
co-operative study. Mult Scler. 2005 Aug;11(4):420-4.
122: Giorelli M, Livrea P, Trojano M. Dopamine fails to regulate activation of
peripheral blood lymphocytes from multiple sclerosis patients: effects of
IFN-beta. J Interferon Cytokine Res. 2005 Jul;25(7):395-406.
123: Chiocchetti A, Comi C, Indelicato M, Castelli L, Mesturini R, Bensi T,
Mazzarino MC, Giordano M, D'Alfonso S, Momigliano-Richiardi P, Liguori M, Zorzon
M, Amoroso A, Trojano M, Monaco F, Leone M, Magnani C, Dianzani U. Osteopontin
gene haplotypes correlate with multiple sclerosis development and progression. J
Neuroimmunol. 2005 Jun;163(1-2):172-8.
124: Roxburgh RH, Seaman SR, Masterman T, Hensiek AE, Sawcer SJ, Vukusic S,
Achiti I, Confavreux C, Coustans M, le Page E, Edan G, McDonnell GV, Hawkins S,
Trojano M, Liguori M, Cocco E, Marrosu MG, Tesser F, Leone MA, Weber A, Zipp F,
Miterski B, Epplen JT, Oturai A, Sørensen PS, Celius EG, Lara NT, Montalban X,
Villoslada P, Silva AM, Marta M, Leite I, Dubois B, Rubio J, Butzkueven H,
Kilpatrick T, Mycko MP, Selmaj KW, Rio ME, Sá M, Salemi G, Savettieri G, Hillert
J, Compston DA. Multiple Sclerosis Severity Score: using disability and disease
duration to rate disease severity. Neurology. 2005 Apr 12;64(7):1144-51.
125: Sisto D, Trojano M, Vetrugno M, Trabucco T, Iliceto G, Sborgia C.
Subclinical visual involvement in multiple sclerosis: a study by MRI, VEPs,
frequency-doubling perimetry, standard perimetry, and contrast sensitivity.
Invest Ophthalmol Vis Sci. 2005 Apr;46(4):1264-8.
126: Ghezzi A, Ruggieri M, Trojano M, Filippi M; ITEMS Study Group. Italian
studies on early-onset multiple sclerosis: the present and the future. Neurol
Sci. 2004 Nov;25 Suppl 4:S346-9.
127: Trojano M, Paolicelli D, Bellacosa A, Fuiani A, Cataldi S, Di Monte E.
Atypical forms of multiple sclerosis or different phases of a same disease?
Neurol Sci. 2004 Nov;25 Suppl 4:S323-5.
128: Amato MP, Grimaud J, Achiti I, Bartolozzi ML, Adeleine P, Hartung HP, Kappos
L, Thompson A, Trojano M, Vukusic S, Confavreux C; Evaluation of the EDMUS system
(EVALUED) Study Group. European validation of a standardized clinical description
of multiple sclerosis. J Neurol. 2004 Dec;251(12):1472-80.
129: Trojano M. Can databasing optimise patient care? J Neurol. 2004 Sep;251
Suppl 5:v79-v82.
130: Savettieri G, Messina D, Andreoli V, Bonavita S, Caltagirone C, Cittadella
R, Farina D, Fazio MC, Girlanda P, Le Pira F, Liguori M, Lugaresi A, Nocentini U,
Reggio A, Salemi G, Tedeschi G, Trojano M, Valentino P, Quattrone A.
Gender-related effect of clinical and genetic variables on the cognitive
impairment in multiple sclerosis. J Neurol. 2004 Oct;251(10):1208-14.
131: Solaro C, Brichetto G, Amato MP, Cocco E, Colombo B, D'Aleo G, Gasperini C,
Ghezzi A, Martinelli V, Milanese C, Patti F, Trojano M, Verdun E, Mancardi GL;
PaIMS Study Group. The prevalence of pain in multiple sclerosis: a multicenter
cross-sectional study. Neurology. 2004 Sep 14;63(5):919-21.
132: Giorelli M, Livrea P, Trojano M. Post-receptorial mechanisms underlie
functional disregulation of beta2-adrenergic receptors in lymphocytes from
Multiple Sclerosis patients. J Neuroimmunol. 2004 Oct;155(1-2):143-9.
133: Patti F, Amato MP, Filippi M, Gallo P, Trojano M, Comi GC. A double blind,
placebo-controlled, phase II, add-on study of cyclophosphamide (CTX) for 24
months in patients affected by multiple sclerosis on a background therapy with
interferon-beta study denomination: CYCLIN. J Neurol Sci. 2004 Aug
15;223(1):69-71.
134: Cosentino M, Zaffaroni M, Giorelli M, Marino F, Ferrari M, Bombelli R,
Rasini E, Trojano M, Lecchini S, Livrea P, Comi G, Frigo G. Adrenergic mechanisms
in multiple sclerosis: the neuro-immune connection? Trends Pharmacol Sci. 2004
Jul;25(7):350-1; author reply 351-2.
135: Ghezzi A, Bergamaschi R, Martinelli V, Trojano M, Tola MR, Merelli E,
Mancardi L, Gallo P, Filippi M, Zaffaroni M, Comi G; Italian Devic's Study Group
(IDESG). Clinical characteristics, course and prognosis of relapsing Devic's
Neuromyelitis Optica. J Neurol. 2004 Jan;251(1):47-52.
136: Liguori M, Cittadella R, Manna I, Valentino P, La Russa A, Serra P, Trojano
M, Messina D, Ruscica F, Andreoli V, Romeo N, Livrea P, Quattrone A. Association
between Synapsin III gene promoter polymorphisms and multiple sclerosis. J
Neurol. 2004 Feb;251(2):165-70.