Pubblicazioni
Genchi VA, Palma G, Sorice GP, D'Oria R, Caccioppoli C, Marrano N, Biondi G, Caruso I, Cignarelli A, Natalicchio A, Laviola L, Giorgino F, Perrini S.
Pharmacological modulation of adaptive thermogenesis: new clues for obesity management?
J Endocrinol Invest. 2023 Nov;46(11):2213-2236. doi:
10.1007/s40618-023-02125-0. Epub 2023 Jun 28. PMID: 37378828; PMCID: PMC10558388.
Maiorino MI, Buzzetti R, Irace C, Laviola L, Napoli N, Pitocco D, Esposito K; LIVE CGM working group. An updated algorithm for an effective choice of continuous glucose monitoring for people with insulin-treated diabetes.
Endocrine. 2023 Nov;82(2):215-225.
doi: 10.1007/s12020-023-03473-w. Epub 2023 Sep 7. PMID: 37676398; PMCID: PMC10543826.
Genchi VA, Palma G, Sorice GP, D'Oria R, Caccioppoli C, Marrano N, Biondi G, Caruso I, Cignarelli A, Natalicchio A, Laviola L, Giorgino F, Perrini S.
Pharmacological modulation of adaptive thermogenesis: new clues for obesity management?
J Endocrinol Invest. 2023 Nov;46(11):2213-2236.
doi: 10.1007/s40618-023-02125-0. Epub 2023 Jun 28. PMID: 37378828; PMCID: PMC10558388.
Caruso I, Di Gioia L, Di Molfetta S, Cignarelli A, Palmer SC, Natale P, Strippoli GFM, Perrini S, Natalicchio A, Laviola L, Giorgino F.
Glucometabolic outcomes of GLP-1 receptor agonist-based therapies in patients with type 2 diabetes: a systematic review and network meta-analysis.
EClinicalMedicine. 2023 Sep 12;64:102181.
doi: 10.1016/j.eclinm.2023.102181. PMID: 37719418; PMCID:PMC10500557.
Di Molfetta S, Laviola L, Natalicchio A, Leonardini A, Cignarelli A, Bonizzoni E, Acmet E, Giorgino F. Evaluation of a digital tool supporting therapeutic decision making for the personalized management of patients with type 2 diabetes not treated with insulin: A pilot study.
Diabetes Res Clin Pract. 2023 Sep;203:110836.
doi: 10.1016/j.diabres.2023.110836. Epub 2023 Jul 20. PMID: 37478979.
Iannone A, Natale P, Palmer SC, Nicolucci A, Rendina M, Giorgino F, Laviola L, Di Leo A, Strippoli GFM. Clinical outcomes associated with drugs for obesity and overweight: A systematic review and network meta-analysis of randomized controlled trials.
Diabetes Obes Metab. 2023 Sep;25(9):2535-2544. doi: 10.1111/dom.15138. Epub 2023 May 31. PMID: 37254688.
Morieri ML, Raz I, Consoli A, Rigato M, Lapolla A, Broglio F, Bonora E, Avogaro A, Fadini GP; DARWIN-FUP network.
Short-term effectiveness of dapagliflozin versus DPP-4 inhibitors in elderly patients with type 2 diabetes:
a multicentre retrospective study.
J Endocrinol Invest. 2023 Jul;46(7):1429-1439. doi: 10.1007/s40618-022-02002-2. Epub 2023 Jan 9. PMID:
36624223; PMCID: PMC10261249.
Di Molfetta S, Caruso I, Cignarelli A, Natalicchio A, Perrini S, Laviola L, Giorgino F.
Professional continuous glucose monitoring in patients with diabetes mellitus: A systematic review and meta-analysis.
Diabetes Obes Metab. 2023 May;25(5):1301-1310. doi: 10.1111/dom.14981. Epub 2023 Feb 14. PMID: 36661362.
Caruso I, Marrano N, Biondi G, Genchi VA, D'Oria R, Sorice GP, Perrini S, Cignarelli A, Natalicchio A, Laviola L, Giorgino F.
Glucagon in type 2 diabetes: Friend or foe?
Diabetes Metab Res Rev. 2023 Mar;39(3):e3609.
doi: 10.1002/dmrr.3609. Epub 2023 Jan 30. PMID: 36637256.
Cignarelli A, Santi D, Genchi VA, Conte E, Giordano F, Di Leo S, Natalicchio A, Laviola L, Giorgino F, Perrini S. Very low-calorie ketogenic diet rapidly augments testosterone levels in non-diabetic obese subjects. Andrology. 2023 Feb;11(2):234-244.
doi: 10.1111/andr.13357. Epub 2022 Dec 14. PMID: 36459060.
Orsi E, Solini A, Penno G, Bonora E, Fondelli C, Trevisan R, Vedovato M, Cavalot F, Lamacchia O, Haxhi J, Nicolucci A, Pugliese G; Renal Insufficiency And Cardiovascular Events (RIACE) Study Group.
Body mass index versus surrogate measures of central adiposity as independent predictors of mortality in type 2 diabetes.
Cardiovasc Diabetol. 2022 Dec 2;21(1):266.
doi: 10.1186/s12933-022-01706-2. PMID: 36461034; PMCID: PMC9716975.
D'Oria R, Genchi VA, Caccioppoli C, Calderoni I, Marrano N, Biondi G, Borrelli A, Di Gioia L, Giorgino F, Laviola L.
Impact of Dysfunctional Adipose Tissue Depots on the Cardiovascular System.
Int J Mol Sci. 2022 Nov 18;23(22):14296.
doi: 10.3390/ijms232214296. PMID: 36430774; PMCID: PMC9695168.
Orsi E, Solini A, Bonora E, Vitale M, Garofolo M, Fondelli C, Trevisan R, Vedovato M, Cavalot F, Laviola L, Morano S, Pugliese G; Renal Insufficiency And Cardiovascular Events (RIACE) Study Group.
Risk of all-cause mortality according to the European Society of Cardiology risk categories in individuals with type 2 diabetes: the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicenter Study.
Acta Diabetol. 2022 Oct;59(10):1369-1381.
doi: 10.1007/s00592-022-01942-8. Epub 2022 Jul 28. PMID: 35902419; PMCID: PMC9402482.
Di Molfetta S, Patruno P, Cormio S, Cignarelli A, Paleari R, Mosca A, Lamacchia O, De Cosmo S, Massa M, Natalicchio A, Perrini S, Laviola L, Giorgino F.
A telemedicine-based approach with real-time transmission of blood glucose data improves metabolic control in insulin-treated diabetes: the DIAMONDS randomized clinical trial.
J Endocrinol Invest. 2022 Sep;45(9):1663-1671.
doi:10.1007/s40618-022-01802-w. Epub 2022 Apr 27. PMID: 35476320; PMCID: PMC9044385.
Biondi G, Marrano N, Dipaola L, Borrelli A, Rella M, D'Oria R, Genchi VA, Caccioppoli C, Porreca I, Cignarelli A, Perrini S, Marchetti P, Vincenti L, Laviola L, Giorgino F, Natalicchio A.
The p66Shc Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic β-Cells Under Lipotoxic Conditions.
Diabetes. 2022 Aug 1;71(8):1763-1771.
doi: 10.2337/db21-1066. PMID:35612429.
Cignarelli A, Genchi VA, Le Grazie G, Caruso I, Marrano N, Biondi G, D'Oria R, Sorice GP, Natalicchio A, Perrini S, Laviola L, Giorgino F.
Mini Review: Effect of GLP-1 Receptor Agonists and SGLT-2 Inhibitors on the Growth Hormone/IGF Axis. Front Endocrinol (Lausanne). 2022 Feb 21;13:846903.
doi:10.3389/fendo.2022.846903. PMID: 35265043; PMCID: PMC8899086.
Caruso I, Cignarelli A, Sorice GP, Natalicchio A, Perrini S, Laviola L, Giorgino F.
Cardiovascular and Renal Effectiveness of GLP-1 Receptor Agonists vs. Other Glucose-Lowering Drugs in Type 2 Diabetes: A Systematic Review and Meta-Analysis of Real-World Studies.
Metabolites. 2022 Feb 15;12(2):183.
doi:10.3390/metabo12020183. PMID: 35208256; PMCID: PMC8879165.
Cignarelli A, Ciavarella A, Barbaro M, Kounaki S, Di Trani A, Falcone VA, Quaranta VN, Natalicchio A, Laviola L, Resta O, Giorgino F, Perrini S.
Postprandial glucose and HbA1c are associated with severity of obstructive sleep apnoea in non-diabetic obese subjects.
J Endocrinol Invest. 2021 Dec;44(12):2741-2748.
doi: 10.1007/s40618-021-01602-8. Epub 2021 Jun 26. PMID:
34173961; PMCID: PMC8572205.
Caruso I, Cignarelli A, Laviola L, Giorgino F.
GLP-1 Receptor Agonists for Cardiovascular Protection: A Matter of Time.
Diabetes Care. 2022 Jan 12:dc211839. doi: 10.2337/dc21-1839. Online ahead of print.
PMID: 35020816
Genchi VA, D'Oria R, Palma G, Caccioppoli C, Cignarelli A, Natalicchio A, Laviola L, Giorgino F, Perrini S.
Impaired Leptin Signalling in Obesity: Is Leptin a New Thermolipokine?
(2021) Int J Mol Sci. Jun 16;22(12):6445.
Cignarelli A, Genchi VA, D'Oria R, Giordano F, Caruso I, Perrini S, Natalicchio A, Laviola L, Giorgino F.
Role of Glucose-Lowering Medications in Erectile Dysfunction.
(2021) J Clin Med. Jun 5;10(11):2501.
Caruso I, Cignarelli A, Laviola L, Giorgino F. Sodium-glucose co-transporter-2 inhibitors and protection from cardiovascular death: Is it all about heart failure?
(2021) Diabetes Obes Metab. May 25. doi: 10.1111/dom.14444.
Bruttomesso D, Boscari F, Lepore G, Noaro G, Cappon G, Girelli A, Bozzetto L, Tumminia A, Grassi G, Sparacino G, Laviola L, Facchinetti A.
A "Slide Rule" to Adjust Insulin Dose Using Trend Arrows in Adults with Type 1 Diabetes: Test in Silico and in Real Life. (2021) Diabetes Ther. May;12(5):1313-1324. doi:
10.1007/s13300-021-01020-2. Epub 2021 Mar 16. PMID: 33725276; PMCID: PMC8099956.
Penno G, Solini A, Orsi E, Bonora E, Fondelli C, Trevisan R, Vedovato M, Cavalot F, Zerbini G, Lamacchia O, Nicolucci A, Pugliese G; Renal Insufficiency And Cardiovascular Events (RIACE) Study Group.
Insulin resistance, diabetic kidney disease, and all-cause mortality in individuals with type 2 diabetes: a prospective cohort study.
(2021) BMC Med. Mar 15;19(1):66. doi:
10.1186/s12916-021-01936-3. PMID: 33715620; PMCID: PMC7962330.
Marrano N, Biondi G, Borrelli A, Cignarelli A, Perrini S, Laviola L, Giorgino F, Natalicchio A.
Irisin and Incretin Hormones: Similarities, Differences, and Implications in Type 2 Diabetes and Obesity
(2021) Biomolecules. Feb 15;11(2):286. doi: 10.3390/biom11020286. PMID: 33671882; PMCID: PMC7918991.
Fadini GP, Disoteo O, Candido R, Di Bartolo P, Laviola L, Consoli A.
Delphi-Based Consensus on Treatment Intensification in Type 2 Diabetes Subjects Failing Basal Insulin Supported Oral Treatment: Focus on Basal Insulin + GLP-1 Receptor Agonist Combination Therapies.
(2021) Diabetes Ther. 2021 Mar;12(3):781-800. doi:
10.1007/s13300-021-01012-2. Epub 2021 Feb 7. PMID: 33550569; PMCID: PMC7947045.
Marrano N, Spagnuolo R, Biondi G, Cignarelli A, Perrini S, Vincenti L, Laviola L, Giorgino F, Natalicchio A.
Effects of Extra Virgin Olive Oil Polyphenols on Beta-Cell Function and Survival.
(2021) Plants (Basel). Feb
3;10(2):286. doi: 10.3390/plants10020286. PMID: 33546278; PMCID: PMC7913337.
Orsi E, Penno G, Solini A, Bonora E, Fondelli C, Trevisan R, Vedovato M, Cavalot F, Morano S, Baroni MG, Nicolucci A, Pugliese G; Renal Insufficiency And Cardiovascular Events (RIACE) Study Group.
Independent association of atherogenic dyslipidaemia with all-cause mortality in individuals with type 2 diabetes and modifying effect of gender: a prospective cohort study.
(2021) Cardiovasc Diabetol. Jan 30;20(1):28. doi: 10.1186/s12933-021-01224-7. PMID: 33516215;
PMCID: PMC7847015.
Laviola L, Porcellati F, Bruttomesso D, Larosa M, Rossi MC, Nicolucci A; RESTORE-1 Study Group.
Comparative Effectiveness of Switching From First-Generation Basal Insulin to Glargine 300 U/ml or Degludec 100 U/ml in Type 1 Diabetes: The RESTORE-1 Study.
(2021) Diabetes Ther. Feb;12(2):509-525. doi:
10.1007/s13300-020-00982-z. Epub 2020 Dec 22. PMID: 33351177; PMCID: PMC7846660.
Caruso I, Di Molfetta S, Guarini F, Giordano F, Cignarelli A, Natalicchio A, Perrini S, Leonardini A, Giorgino F, Laviola L. Reduction of hypoglycaemia, lifestyle modifications and psychological distress during lockdown following SARS-CoV-2 outbreak in type 1 diabetes.
(2020) Diabetes Metab Res Rev. 2020 Sep
11:e3404. doi: 10.1002/dmrr.3404. Epub ahead of print. PMID: 32918324.
Cignarelli A, Sansone A, Caruso I, Perrini S, Natalicchio A, Laviola L, Jannini EA, Giorgino F.
Diabetes in the Time of COVID-19: A Twitter-Based Sentiment Analysis.
(2020) J Diabetes Sci Technol. Nov;14(6):1131-1132. doi:
10.1177/1932296820945297. Epub 2020 Aug 7. PMID: 32762346; PMCID: PMC7645122.
Penno G, Orsi E, Solini A, Bonora E, Fondelli C, Trevisan R, Vedovato M, Cavalot F, Gruden G, Laviola L, Nicolucci A, Pugliese G; Renal Insufficiency And Cardiovascular Events (RIACE) Study Group.
Renal hyperfiltration is independently associated with increased all-cause mortality in individuals with type 2 diabetes: a prospective cohort study.
(2020) BMJ Open Diabetes Res Care. Jul;8(1):e001481. doi: 10.1136/bmjdrc-2020-001481. PMID: 32665314; PMCID:
PMC7365485.
Marrano N, Biondi G, Cignarelli A, Perrini S, Laviola L, Giorgino F, Natalicchio A.
Functional loss of pancreatic islets in type 2 diabetes: How can we halt it?
(2020) Metabolism. Sep;110:154304. doi: 10.1016/j.metabol.2020.154304.
Epub 2020 Jun 27. PMID: 32599081.
Castellana M, Parisi C, Di Molfetta S, Di Gioia L, Natalicchio A, Perrini S, Cignarelli A, Laviola L, Giorgino F.
Efficacy and safety of flash glucose monitoring in patients with type 1 and type 2 diabetes: a systematic review and
meta-analysis.
(2020) BMJ Open Diabetes Res Care. Jun;8(1):e001092. doi:
10.1136/bmjdrc-2019-001092. PMID: 32487593; PMCID: PMC7265013.
Caruso, I., Cignarelli, A., Natalicchio, A., Perrini, S., Laviola, L., Giorgino, F.
Commentary: Glucose control: Not just a bystander in GLP-1RA-mediated cardiovascular protection
(2020) Metabolism: Clinical and Experimental, 109, art. no. 154272.
Irace, C., Cutruzzolà, A., Nuzzi, A., Assaloni, R., Brunato, B., Pitocco, D., Tartaglione, L., Di Molfetta, S., Cignarelli, A., Laviola, L., Citro, G., Lovati, E., Gnasso, A., Tweden, K.S., Kaufman, F.R.
Clinical use of a 180-day implantable glucose sensor improves glycated haemoglobin and time in range in patients with type 1 diabetes
(2020) Diabetes, Obesity and Metabolism, 22 (7), pp. 1056-1061.
Natalicchio, A., Marrano, N., Biondi, G., Dipaola, L., Spagnuolo, R., Cignarelli, A., Perrini, S., Laviola, L., Giorgino, F.
Irisin increases the expression of anorexigenic and neurotrophic genes in mouse brain
(2020) Diabetes/Metabolism Research and Reviews, 36 (3), art. no. e3238, .
Perrini, S., Porro, S., Nigro, P., Cignarelli, A., Caccioppoli, C., Genchi, V.A., Martines, G., De Fazio, M., Capuano, P., Natalicchio, A., Laviola, L., Giorgino, F.
Reduced SIRT1 and SIRT2 expression promotes adipogenesis of human visceral adipose stem cells and associates with accumulation of visceral fat in human obesity
(2020) International Journal of Obesity, 44 (2), pp. 307-319.
D'Oria, R., Schipani, R., Leonardini, A., Natalicchio, A., Perrini, S., Cignarelli, A., Laviola, L., Giorgino, F.
The Role of Oxidative Stress in Cardiac Disease: From Physiological Response to Injury Factor
(2020) Oxidative Medicine and Cellular Longevity, 2020, art. no. 5732956, .
Castellana, M., Cignarelli, A., Brescia, F., Perrini, S., Natalicchio, A., Laviola, L., Giorgino, F.
Efficacy and safety of GLP-1 receptor agonists as add-on to SGLT2 inhibitors in type 2 diabetes mellitus: A meta-analysis
(2019) Scientific Reports, 9 (1), art. no. 19351, .
Conserva, F., Barozzino, M., Pesce, F., Divella, C., Oranger, A., Papale, M., Sallustio, F., Simone, S., Laviola, L., Giorgino, F., Gallone, A., Pontrelli, P., Gesualdo, L.
Urinary miRNA-27b-3p and miRNA-1228-3p correlate with the progression of Kidney Fibrosis in Diabetic Nephropathy
(2019) Scientific Reports, 9 (1), art. no. 11357, .
Cignarelli, A., Castellana, M., Castellana, G., Perrini, S., Brescia, F., Natalicchio, A., Garruti, G., Laviola, L., Resta, O., Giorgino, F.
Effects of CPAP on Testosterone Levels in Patients With Obstructive Sleep Apnea: A Meta-Analysis Study
(2019) Frontiers in Endocrinology, 10, art. no. 551, .
Bruttomesso, D., Laviola, L., Avogaro, A., Bonora, E., Del Prato, S., Frontoni, S., Orsi, E., Rabbone, I., Sesti, G., Purrello, F., of the Italian Diabetes Society (SID)
The use of real time continuous glucose monitoring or flash glucose monitoring in the management of diabetes: A consensus view of Italian diabetes experts using the Delphi method
(2019) Nutrition, Metabolism and Cardiovascular Diseases, 29 (5), pp. 421-431.
Solini, A., Penno, G., Orsi, et al.
Is resistant hypertension an independent predictor of all-cause mortality in individuals with type 2 diabetes? A prospective cohort study
(2019) BMC Medicine, 17 (1), art. no. 83, .
Castellana, M., Cignarelli, A., Brescia, F., Laviola, L., Giorgino, F.
GLP-1 receptor agonist added to insulin versus basal-plus or basal-bolus insulin therapy in type 2 diabetes: A systematic review and meta-analysis
(2019) Diabetes/Metabolism Research and Reviews, 35 (1), art. no. e3082, .
Cignarelli, A., Genchi, V.A., Perrini, S., Natalicchio, A., Laviola, L., Giorgino, F.
Insulin and insulin receptors in adipose tissue development
(2019) International Journal of Molecular Sciences, 20 (3), art. no. 759, .
Di Lenarda, A., Candido, R., Anichini, R., Caldarola, P., Comeglio, M., Giordano, R., Laviola, L., Perseghin, G., Polizzi, G.M., Provenzano, V., Ricci, R., Specchia, G., Zicari, S.
Collaborative synergy in the management of diabetic patients with recent acute coronary syndrome [Sinergia collaborativa nella gestione del paziente diabetico con recente sindrome coronarica acuta]
(2019) Giornale Italiano di Cardiologia, 20 (6), pp. 351-360.
Cignarelli, A., Genchi, V.A., Caruso, I., Natalicchio, A., Perrini, S., Laviola, L., Giorgino, F.
Diabetes and cancer: Pathophysiological fundamentals of a ‘dangerous affair’
(2018) Diabetes Research and Clinical Practice, 143, pp. 378-388.
Pontrelli, P., Oranger, A., Barozzino, M., Divella, C., Conserva, F., Fiore, M.G., Rossi, R., Papale, M., Castellano, G., Simone, S., Laviola, L., Giorgino, F., Piscitelli, D., Gallone, A., Gesualdo, L.
Deregulation of autophagy under hyperglycemic conditions is dependent on increased lysine 63 ubiquitination: a candidate mechanism in the progression of diabetic nephropathy
(2018) Journal of Molecular Medicine, 96 (7), pp. 645-659.
Penno, G., Solini, A., Bonora, E., Orsi, E., Fondelli, C., Zerbini, G., Trevisan, R., Vedovato, M., Cavalot, F., Laviola, L., Nicolucci, A., Pugliese, G., for the Renal Insufficiency and Cardiovascular Events (RIACE) Study Group
Defining the contribution of chronic kidney disease to all-cause mortality in patients with type 2 diabetes: the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicenter Study
(2018) Acta Diabetologica, 55 (6), pp. 603-612.
Incalza, M.A., D'Oria, R., Natalicchio, A., Perrini, S., Laviola, L., Giorgino, F.
Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases
(2018) Vascular Pharmacology, 100, pp. 1-19.
Lepore, G., Bonfanti, R., Bozzetto, L., Di Blasi, V., Girelli, A., Grassi, G., Iafusco, D., Laviola, L., et al.
Metabolic control and complications in Italian people with diabetes treated with continuous subcutaneous insulin infusion
(2018) Nutrition, Metabolism and Cardiovascular Diseases, 28 (4), pp. 335-342.
Vitale, M., Masulli, M., Rivellese, A.A., et al.
(2018) European Journal of Nutrition, 57 (2), pp. 679-688.
Lisco, G., Cicco, G., Cignarelli, A., Garruti, G., Laviola, L., Giorgino, F.
Computerized video-capillaroscopy alteration related to diabetes mellitus and its complications
(2018) Advances in Experimental Medicine and Biology, 1072, pp. 363-368.
Vitale, M., Vaccaro, O., Masulli, M., Bonora, E., Del Prato, S., Giorda, C.B., Nicolucci, A., Squatrito, S., Auciello, S., Babini, A.C., Bani, L., Buzzetti, R., Cannarsa, E., Cignarelli, M., Cigolini, M., Clemente, G., Cocozza, S., Corsi, L., D'Angelo, F., Dall'Aglio, E., Di Cianni, G., Fontana, L., Gregori, G., Grioni, S., Giordano, C., Iannarelli, R., Iovine, C., Lapolla, A., Lauro, D., Laviola, L., Mazzucchelli, C., Signorini, S., Tonutti, L., Trevisan, R., Zamboni, C., Riccardi, G., Rivellese, A.A., the TOSCA.IT Study Group
Polyphenol intake and cardiovascular risk factors in a population with type 2 diabetes: The TOSCA.IT study
(2017) Clinical Nutrition, 36 (6), pp. 1686-1692.
Natalicchio, A., Marrano, N., Biondi, G., Spagnuolo, R., Labarbuta, R., Porreca, I., Cignarelli, A., Bugliani, M., Marchetti, P., Perrini, S., Laviola, L., Giorgino, F.
The myokine irisin is released in response to saturated fatty acids and promotes pancreatic β-cell survival and insulin secretion
(2017) Diabetes, 66 (11), pp. 2849-2856.
Vaccaro, O., Masulli, M., Nicolucci, A., et al.
Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial
(2017) The Lancet Diabetes and Endocrinology, 5 (11), pp. 887-897.
D'Oria, R., Laviola, L., Giorgino, F., Unfer, V., Bettocchi, S., Scioscia, M.
PKB/Akt and MAPK/ERK phosphorylation is highly induced by inositols: Novel potential insights in endothelial dysfunction in preeclampsia
(2017) Pregnancy Hypertension, 10, pp. 107-112.
Averna, M., Cefalù, A.B., Casula, M., et al.
Familial hypercholesterolemia: The Italian Atherosclerosis Society Network (LIPIGEN)
(2017) Atherosclerosis Supplements, 29, pp. 11-16.
Pirillo, A., Garlaschelli, K., Arca, M., et al.
Spectrum of mutations in Italian patients with familial hypercholesterolemia: New results from the LIPIGEN study
(2017) Atherosclerosis Supplements, 29, pp. 17-24.
Perrini, S., Cignarelli, A., Quaranta, V.N., Falcone, V.A., Kounaki, S., Porro, S., Ciavarella, A., Ficarella, R., Barbaro, M., Genchi, V.A., Nigro, P., Carratù, P., Natalicchio, A., Laviola, L., Resta, O., Giorgino, F.
Correction of intermittent hypoxia reduces inflammation in obese subjects with obstructive sleep apnea
(2017) JCI insight, 2 (17), .
Leonardini, A., D'Oria, R., Incalza, M.A., Caccioppoli, C., Buccheri, V.A., Cignarelli, A., Paparella, D., Margari, V., Natalicchio, A., Perrini, S., Giorgino, F., Laviola, L.
GLP-1 receptor activation inhibits palmitate-induced apoptosis via ceramide in human cardiac progenitor cells
(2017) Journal of Clinical Endocrinology and Metabolism, 102 (11), pp. 4136-4147.
Rossi, L., Nicoletti, M.C., Carmosino, M., Mastrofrancesco, L., Di Franco, A., Indrio, F., Lella, R., Laviola, L., Giorgino, F., Svelto, M., Gesualdo, L., Procino, G.
Urinary Excretion of Kidney Aquaporins as Possible Diagnostic Biomarker of Diabetic Nephropathy
(2017) Journal of Diabetes Research, 2017, art. no. 4360357, .
Pontrelli, P., Conserva, F., Papale, M., Oranger, A., Barozzino, M., Vocino, G., Rocchetti, M.T., Gigante, M., Castellano, G., Rossini, M., Simone, S., Laviola, L., Giorgino, F., Grandaliano, G., Di Paolo, S., Gesualdo, L.
Lysine 63 ubiquitination is involved in the progression of tubular damage in diabetic nephropathy
(2017) FASEB Journal, 31 (1), pp. 308-319.
Laviola, L., Bonomo, M.
Physical activity for people with diabetes [Attività fisica per la persona con diabete]
(2016) Giornale Italiano di Diabetologia e Metabolismo, 36 (2), pp. 55-56.
Bonfanti, R., Lepore, G., Bozzetto, L., Corsi, A., Di Blasi, V., Girelli, A., Grassi, G., Iafusco, D., Rabbone, I., Schiaffini, R., Laviola, L., Bruttomesso, D.
Survey on the use of insulin pumps in Italy: comparison between pediatric and adult age groups (IMITA study)
(2016) Acta Diabetologica, 53 (3), pp. 403-412.
Natalicchio, A., Biondi, G., Marrano, N., Labarbuta, R., Tortosa, F., Spagnuolo, R., D'Oria, R., Carchia, E., Leonardini, A., Cignarelli, A., Perrini, S., Laviola, L., Giorgino, F.
Long-term exposure of pancreatic β-cells to palmitate results in SREBP-1C-dependent decreases in GLP-1 receptor signaling via CREB and AKT and insulin secretory response
(2016) Endocrinology, 157 (6), pp. 2243-2258.
Cignarelli, A., Perrini, S., Nigro, P., Ficarella, R., Barbaro, M., Peschechera, A., Porro, S., Natalicchio, A., Laviola, L., Puglisi, F., Giorgino, F.
Long-acting insulin analog detemir displays reduced effects on adipocyte differentiation of human subcutaneous and visceral adipose stem cells
(2016) Nutrition, Metabolism and Cardiovascular Diseases, 26 (4), pp. 333-344.
Laviola, L., Porcellati, F., Gentile, S.
Awareness, identification and prevention of insulin injection-associated lipodystrophies [Lipodistrofie da iniezione di insulina: Conoscerle, riconoscerle, prevenirle]
(2016) Giornale Italiano di Diabetologia e Metabolismo, 36 (1), pp. 32-36.
Notarnicola, A., Maccagnano, G., Tafuri, S., Moretti, L., Laviola, L., Moretti, B.
Epidemiology of diabetes mellitus in the fragility fracture population of a region of Southern Italy
(2016) Journal of biological regulators and homeostatic agents, 30 (1), pp. 297-302.
Natalicchio, A., Tortosa, F., Labarbuta, R., Biondi, G., Marrano, N., Carchia, E., Leonardini, A., Cignarelli, A., Bugliani, M., Marchetti, P., Fadini, G.P., Giorgio, M., Avogaro, A., Perrini, S., Laviola, L., Giorgino, F.
Erratum to: The p66Shc redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells [Diabetologia, DOI 10.1007/s00125-015-3563-2]
(2015) Diabetologia, 58 (11), p. 2682.
Penno, G., Solini, A., Zoppini, G., Fondelli, C., Trevisan, R., Vedovato, M., Cavalot, F., Gruden, G., Lamacchia, O., Laviola, L., Orsi, E., Pugliese, G.
Independent correlates of urinary albumin excretion within the normoalbuminuric range in patients with type 2 diabetes: The Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicentre Study
(2015) Acta Diabetologica, 52 (5), pp. 971-981.
Natalicchio, A., Tortosa, F., Labarbuta, R., Biondi, G., Marrano, N., Carchia, E., Leonardini, A., Cignarelli, A., Bugliani, M., Marchetti, P., Fadini, G.P., Giorgio, M., Avogaro, A., Perrini, S., Laviola, L., Giorgino, F.
The p66Shc redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells
(2015) Diabetologia, 58 (6), pp. 1260-1271.
Bruttomesso, D., Laviola, L., Lepore, G., et al..
Subcutaneous insulin infusion (CSII) in italy: The third national survey [La terapia insulinica sottocutanea continua (CSII) in Italia. Terza indagine nazionale]
(2015) Giornale Italiano di Diabetologia e Metabolismo, 35 (2), pp. 121-129.
Peeters, S.A., Engelen, L., Buijs, J., et al.
Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: The EURODIAB Prospective Complications Study
(2015) Cardiovascular Diabetology, 14 (1), art. no. 31, .
Bruttomesso, D., Laviola, L., Lepore, G., et al.
Continuous subcutaneous insulin infusion in Italy: Third national survey
(2015) Diabetes Technology and Therapeutics, 17 (2), pp. 96-104.
Ficarella, R., Laviola, L., Giorgino, F.
Lipodystrophic Diabetes Mellitus: a Lesson for Other Forms of Diabetes?
(2015) Current Diabetes Reports, 15 (3), 10 p.
Perrini, S., Tortosa, F., Natalicchio, A., Pacelli, C., Cignarelli, A., Palmieri, V.O., Caccioppoli, C., De Stefano, F., Porro, S., Leonardini, A., Ficarella, R., De Fazio, M., Cocco, T., Puglisi, F., Laviola, L., Palasciano, G., Giorgino, F.
The p66shcprotein controls redox signaling and oxidation-dependent DNA damage in human liver cells
(2015) American Journal of Physiology - Gastrointestinal and Liver Physiology, 309 (10), pp. 826-840.
Lucchin, L., Fusco, M.A., Caretto, A., et al.
Manifesto of the critical issues in preventive and clinical nutrition: The first ten Italian challenges (2015-2018) [Manifesto delle criticità in Nutrizione clinica e preventiva: Le prime dieci sfide Italiane (2015-2018)]
(2015) Recenti Progressi in Medicina, 106 (6), pp. 1-34.
Pugliese, G., Solini, A., Bonora, E., Orsi, E., Zerbini, G., Fondelli, C., Gruden, G., Cavalot, F., Lamacchia, O., Trevisan, R., Vedovato, M., Penno, G., Laviola, L., Nicolucci, A., Cosmo, S.D., Morano, S., Pugliese, F., Salvi, L., Bollanti, L., Bazuro, A., Cavallo-Perin, P., Lorenzati, B., Trovati, M., Anfossi, G., Chirio, M., Martina, V., Maestroni, S., Montefusco, L., Zimbalatti, D., Pontiroli, A., Veronelli, A., Zecchini, B., Arosio, M., Dolci, A., Corsi, A., Zoppini, G., Avogaro, A., Pagnin, E., Pucci, L., Lucchesi, D., Russo, E., Garofolo, M., Dotta, F., Nigi, L., Gatti, A., Buzzetti, R., Foffi, C., Cignarelli, M., Pinnelli, S., Monaco, L., Giorgino, F., Perrini, S., Sesti, G., Andreozzi, F., Baroni, M.G., Frau, G.
Distribution of cardiovascular disease and retinopathy in patients with type 2 diabetes according to different classification systems for chronic kidney disease: A cross-sectional analysis of the renal insufficiency and cardiovascular events (RIACE) Italian multicenter study
(2014) Cardiovascular Diabetology, 13 (1), art. no. 59, .
Ametrano, A.G., Losurdo, F., Strippoli, D., De Tullio, A., Ippolito, C., Laviola, L., Bellomo Damato, A., Giorgino, F.
A case of fasting hypoglycemia and postprandial hyperglycemia by insulin antibodies [Un caso di ipoglicemia a digiuno e iperglicemia postprandiale da anticorpi anti-insulina]
(2014) Giornale Italiano di Diabetologia e Metabolismo, 34 (1), pp. 32-35.
Laviola, L., Orlando, M.R., Incalza, M.A., Caccioppoli, C., Melchiorre, M., Leonardini, A., Cignarelli, A., Tortosa, F., Labarbuta, R., Martemucci, S., Pacelli, C., Cocco, T., Perrini, S., Natalicchio, A., Giorgino, F.
TNFα signals via p66Shcto induce E-selectin, promote leukocyte transmigration and enhance permeability in human endothelial cells
(2013) PLoS ONE, 8 (12), art. no. e81930, .
Natalicchio, A., Labarbuta, R., Tortosa, F., Biondi, G., Marrano, N., Peschechera, A., Carchia, E., Orlando, M.R., Leonardini, A., Cignarelli, A., Marchetti, P., Perrini, S., Laviola, L., Giorgino, F.
Exendin-4 protects pancreatic beta cells from palmitate-induced apoptosis by interfering with GPR40 and the MKK4/7 stress kinase signalling pathway
(2013) Diabetologia, 56 (11), pp. 2456-2466.
Penno, G., Solini, A., Bonora, E., Fondelli, C., Orsi, E., Zerbini, G., Morano, S., Cavalot, F., Lamacchia, O., Laviola, L., Nicolucci, A., Pugliese, G.
HbA1c variability as an independent correlate of nephropathy, but not retinopathy, in patients with type 2 diabetes: The renal insufficiency and cardiovascular events (RIACE) Italian Multicenter Study
(2013) Diabetes Care, 36 (8), pp. 2301-2310.
Penno, G., Solini, A., Bonora, E., Fondelli, C., Orsi, E., Zerbini, G., Trevisan, R., Vedovato, M., Gruden, G., Laviola, L., Nicolucci, A., Pugliese, G.
Gender differences in cardiovascular disease risk factors, treatments and complications in patients with type 2 diabetes: The RIACE Italian multicentre study
(2013) Journal of Internal Medicine, 274 (2), pp. 176-191.
Perrini, S., Ficarella, R., Picardi, E., Cignarelli, A., Barbaro, M., Nigro, P., Peschechera, A., Palumbo, O., Carella, M., De Fazio, M., Natalicchio, A., Laviola, L., Pesole, G., Giorgino, F.
Differences in Gene Expression and Cytokine Release Profiles Highlight the Heterogeneity of Distinct Subsets of Adipose Tissue-Derived Stem Cells in the Subcutaneous and Visceral Adipose Tissue in Humans
(2013) PLoS ONE, 8 (3), art. no. e57892, .
Giorgino, F., Leonardini, A., Laviola, L.
Cardiovascular disease and glycemic control in type 2 diabetes: Now that the dust is settling from large clinical trials
(2013) Annals of the New York Academy of Sciences, 1281 (1), pp. 36-50.
Ciccone, M.M., Marchese, A., Generali, A., Loiodice, C., Cortese, F., Carbonara, R., Scicchitano, P., Laviola, L., Giorgino, F.
Interventional therapy in diabetic foot: Risk factors, clinical events and prognosis at one year follow-up (a study of 103 cases)
(2012) Pakistan Journal of Biological Sciences, 15 (16), pp. 789-794.
Laviola, L., Leonardini, A., Melchiorre, M., Orlando, M.R., Peschechera, A., Bortone, A., Paparella, D., Natalicchio, A., Perrini, S., Giorgino, F.
Glucagon-like peptide-1 counteracts oxidative stress-dependent apoptosis of human cardiac progenitor cells by inhibiting the activation of the c-Jun N-terminal protein kinase signaling pathway
(2012) Endocrinology, 153 (12), pp. 5770-5781.
Penno, G., Solini, A., Zoppini, G., Orsi, E., Zerbini, G., Trevisan, R., Gruden, G., Cavalot, F., Laviola, L., Morano, S., Nicolucci, A., Pugliese, G.
Rate and determinants of association, between advanced retinopathy and chronic kidney disease in patients with type 2 diabetes: The renal insufficiency and cardiovascular events (RIACE) Italian multicenter study
(2012) Diabetes Care, 35 (11), pp. 2317-2323.
Natalicchio, A., Tortosa, F., Perrini, S., Laviola, L., Giorgino, F.
P66Shc, a multifaceted protein linking Erk signalling, glucose metabolism, and oxidative stress
(2011) Archives of Physiology and Biochemistry, 117 (3), pp. 116-124.
Bellomo Damato, A., Stefanelli, G., Laviola, L., Giorgino, R., Giorgino, F.
Nateglinide provides tighter glycaemic control than glyburide in patients with Type2 diabetes with prevalent postprandial hyperglycaemia
(2011) Diabetic Medicine, 28 (5), pp. 560-566.
Giorgino, F., Leonardini, A., Natalicchio, A., Laviola, L.
Multifactorial intervention in Type 2 diabetes: The promise of incretin-based therapies
(2011) Journal of Endocrinological Investigation, 34 (1), pp. 69-77.
Penno, G., Solini, A., Bonora, E., Fondelli, C., Orsi, E., Zerbini, G., Trevisan, R., Vedovato, M., Gruden, G., Cavalot, F., Cignarelli, M., Laviola, L., Morano, S., Nicolucci, A., Pugliese, G.
Clinical significance of nonalbuminuric renal impairment in type 2 diabetes
(2011) Journal of Hypertension, 29 (9), pp. 1802-1809.
Laviola, L., Ficarella, R., Patruno, P., Barbaro, M., Perrini, S., Bellomo Damato, A., Giorgino, F.
Type 2 diabetes with partial lipodystrophy: Favorable metabolic effects of the use of pioglitazone [Diabete di tipo 2 con lipodistrofia parziale: Effetti metabolici favorevoli dell'impiego di pioglitazone]
(2010) Giornale Italiano di Diabetologia e Metabolismo, 30 (4), pp. 188-191.
Cignarelli, A., Melchiorre, M., Peschechera, A., Conserva, A., Renna, L.A., Miccoli, S., Natalicchio, A., Perrini, S., Laviola, L., Giorgino, F.
Role of UBC9 in the regulation of the adipogenic program in 3T3-L1 adipocytes
(2010) Endocrinology, 151 (11), pp. 5255-5266.
Perrini, S., Laviola, L., Carreira, M.C., Cignarelli, A., Natalicchio, A., Giorgino, F.
The GH/IGF1 axis and signaling pathways in the muscle and bone: Mechanisms underlying age-related skeletal muscle wasting and osteoporosis
(2010) Journal of Endocrinology, 205 (3), pp. 201-210.
Natalicchio, A., De Stefano, F., Orlando, M.R., Melchiorre, M., Leonardini, A., Cignarelli, A., Labarbuta, R., Marchetti, P., Perrini, S., Laviola, L., Giorgino, F.
Exendin-4 prevents c-Jun N-terminal protein kinase activation by Tumor Necrosis Factor-α (TNFα) and inhibits TNFα-induced apoptosis in insulin-secreting cells
(2010) Endocrinology, 151 (5), pp. 2019-2029.
Carreira, M.C., Perrini, S., Cignarelli, A., Ficarella, R., Laviola, L., Giorgino, F.
Adipose tissue precursor cells
(2010) Obesity and Metabolism, 6 (1), pp. 10-18.
de Cillis, E., Leonardini, A., Laviola, L., Giorgino, F., Tupputi Schinosa, L.L., Bortone, A.S.
Different gene expression in human heart tissue and progenitor cells from control and diabetic subjects: relevance to the pathogenesis of human diabetic cardiomyopathy.
(2010) Surgical technology international, 19, pp. 165-174.
Giorgino, F., Leonardini, A., Laviola, L., Perrini, S., Natalicchio, A.
Cross-Talk between PPARγ and insulin signaling and modulation of Insulin Sensitivity
(2009) PPAR Research, art. no. 818945, .
Perrini, S., Cignarelli, A., Ficarella, R., Laviola, L., Giorgino, F.
Human adipose tissue precursor cells: A new factor linking regulation of fat mass to obesity and type 2 diabetes?
(2009) Archives of Physiology and Biochemistry, 115 (4), pp. 218-226.
Natalicchio, A., De Stefano, F., Perrini, S., Laviola, L., Cignarelli, A., Caccioppoli, C., Quagliara, A., Melchiorre, M., Leonardini, A., Conserva, A., Giorgino, F.
Involvement of the p66Shc protein in glucose transport regulation in skeletal muscle myoblasts
(2009) American Journal of Physiology - Endocrinology and Metabolism, 296 (2), pp. E228-E237.
Laviola, L., Natalicchio, A., Perrini, S., Giorgino, F.
Abnormalities of IGF-I signaling in the pathogenesis of diseases of the bone, brain, and fetoplacental unit in humans
(2008) American Journal of Physiology - Endocrinology and Metabolism, 295 (5), pp. E991-E999.
Perrini, S., Leonardini, A., Laviola, L., Giorgino, F.
Biological specificity of visceral adipose tissue and therapeutic intervention
(2008) Archives of Physiology and Biochemistry, 114 (4), pp. 277-286.
Perrini, S., Natalicchio, A., Laviola, L., Cignarelli, A., Melchiorre, M., De Stefano, F., Caccioppoli, C., Leonardini, A., Martemucci, S., Belsanti, G., Miccoli, S., Ciampolillo, A., Corrado, A., Cantatore, F.P., Giorgino, R., Giorgino, F.
Abnormalities of insulin-like growth factor-I signaling and impaired cell proliferation in osteoblasts from subjects with osteoporosis
(2008) Endocrinology, 149 (3), pp. 1302-1313.
Perrini, S., Carreira, M.C., Conserva, A., Laviola, L., Giorgino, F.
Metabolic implications of growth hormone therapy.
(2008) Journal of endocrinological investigation, 31 (9 Suppl), pp. 79-84.
Perrini, S., Laviola, L., Cignarelli, A., Melchiorre, M., De Stefano, F., Caccioppoli, C., Natalicchio, A., Orlando, M.R., Garruti, G., De Fazio, M., Catalano, G., Memeo, V., Giorgino, R., Giorgino, F.
Fat depot-related differences in gene expression, adiponectin secretion, and insulin action and signalling in human adipocytes differentiated in vitro from precursor stromal cells
(2008) Diabetologia, 51 (1), pp. 155-164.
Giorgino, F., Natalicchio, A., Leonardini, A., Laviola, L.
Exploiting the pleiotropic actions of GLP-1 for the management of type 2 diabetes mellitus and its complications
(2007) Diabetes Research and Clinical Practice, 78 (3 SUPPL.), pp. S59-S67.
Laviola, L., Natalicchio, A., Giorgino, F.
The IGF-I signaling pathway
(2007) Current Pharmaceutical Design, 13 (7), pp. 663-669.
Giorgino, F., Laviola, L., Leonardini, A., Natalicchio, A.
GLP-1: a new approach for type 2 diabetes therapy
(2006) Diabetes Research and Clinical Practice, 74 (SUPPL. 2), pp. S152-S155.
Laviola, L., Perrini, S., Cignarelli, A., Natalicchio, A., Leonardini, A., De Stefano, F., Cuscito, M., De Fazio, M., Memeo, V., Neri, V., Cignarelli, M., Giorgino, R., Giorgino, F.
Insulin signaling in human visceral and subcutaneous adipose tissue in vivo
(2006) Diabetes, 55 (4), pp. 952-961.
Laviola, L., Perrini, S., Cignarelli, A., Giorgino, F.
Insulin signalling in human adipose tissue
(2006) Archives of Physiology and Biochemistry, 112 (2), pp. 82-88.
Laviola, L., Cignarelli, A., Giorgino, F.
Clinical view on the need to develop new anti-diabetic drugs
(2005) Current Medicinal Chemistry: Immunology, Endocrine and Metabolic Agents, 5 (6), pp. 469-474.
Giorgino, F., Laviola, L., Leonardini, A.
Pathophysiology of type 2 diabetes: Rationale for different oral antidiabetic treatment strategies
(2005) Diabetes Research and Clinical Practice, 68 (SUPPL. 1), pp. S22-S29.
Laviola, L., Perrini, S., Belsanti, G., Natalicchio, A., Montrone, C., Leonardini, A., Vimercati, A., Scioscia, M., Selvaggi, L., Giorgino, R., Greco, P., Giorgino, F.
Intrauterine growth restriction in humans is associated with abnormalities in placental insulin-like growth factor signaling
(2005) Endocrinology, 146 (3), pp. 1498-1505.
Giorgino, F., Laviola, L., Eriksson, J.W.
Regional differences of insulin action in adipose tissue: Insights from in vivo and in vitro studies
(2005) Acta Physiologica Scandinavica, 183 (1), pp. 13-30.
Perrini, S., Laviola, L., Natalicchio, A., Giorgino, F.
Associated hormonal declines in aging: DHEAS.
(2005) Journal of endocrinological investigation, 28 (3 Suppl), pp. 85-93.
Natalicchio, A., Laviola, L., De Tullio, C., Renna, L.A., Montrone, C., Perrini, S., Valenti, G., Procino, G., Svelto, M., Giorgino, F.
Role of the p66Shc isoform in insulin-like growth factor I receptor signaling through MEK/Erk and regulation of actin cytoskeleton in rat myoblasts
(2004) Journal of Biological Chemistry, 279 (42), pp. 43900-43909.
Giorgino, F., Laviola, L., Cavallo Perin, P., Solnica, B., Fuller, J., Chaturvedi, N.
Factors associated with progression to macroalbuminuria in microalbuminuric Type 1 diabetic patients: The EURODIAB Prospective Complications Study
(2004) Diabetologia, 47 (6), pp. 1020-1028.
Perrini, S., Natalicchio, A., Laviola, L., Belsanti, G., Montrone, C., Cignarelli, A., Minielli, V., Grano, M., De Pergola, G., Giorgino, R., Giorgino, F.
Dehydroepiandrosterone Stimulates Glucose Uptake in Human and Murine Adipocytes by Inducing GLUT1 and GLUT4 Translocation to the Plasma Membrane
(2004) Diabetes, 53 (1), pp. 41-52.
Giovannone, B., Lee, E., Laviola, L., Giorgino, F., Cleveland, K.A., Smith, R.J.
Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling
(2003) Journal of Biological Chemistry, 278 (34), pp. 31564-31573.
Laviola, L., Belsanti, G., Davalli, A.M., Napoli, R., Perrini, S., Weir, G.C., Giorgino, R., Giorgino, F.
Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart
(2001) Diabetes, 50 (12), pp. 2709-2720.
Giorgino, F., De Robertis, O., Laviola, L., Montrone, C., Perrini, S., McCowen, K.C., Smith, R.J.
The sentrin-conjugating enzyme mUbc9 interacts with GLUT4 and GLUT1 glucose transporters and regulates transporter levels in skeletal muscle cells
(2000) Proceedings of the National Academy of Sciences of the United States of America, 97 (3), pp. 1125-1130.
Giorgino, F., Logoluso, F., Davalli, A.M., Napoli, R., Laviola, L., Hirshman, M.F., Horton, E.S., Weir, G.C., Smith, R.J.
Islet transplantation restores normal levels of insulin receptor and substrate tyrosine phosphorylation and phosphatidylinositol 3-kinase activity in skeletal muscle and myocardium of streptozocin-induced diabetic rats
(1999) Diabetes, 48 (4), pp. 801-812.
Laviola, L., Giorgino, F., Chow, J.C., Baquero, J.A., Hansen, H., Ooi, J., Zhu, J., Riedel, H., Smith, R.J.
The adapter protein Grb10 associates preferentially with the insulin receptor as compared with the IGF-I receptor in mouse fibroblasts
(1997) Journal of Clinical Investigation, 99 (5), pp. 830-837.
Hansen, H., Svensson, U., Zhu, J., Laviola, L., Giorgino, F., Wolf, G., Smith, R.J., Riedel, H.
Interaction between the Grb10 SH2 domain and the insulin receptor carboxyl terminus
(1996) Journal of Biological Chemistry, 271 (15), pp. 8882-8886.
Giorgino, F., Montrone, C., de Robertis, O., Laviola, L., McCowen, K., Smith, R.J.
The carboxy-terminal domain of the GLUT4 glucose transporter interacts with a novel E2 ubiquitin-conjugating enzyme identified by two-hybrid cloning
(1996) Experimental and Clinical Endocrinology and Diabetes, 104, pp. 29-31.
Chow, J.C., Ling, P.R., Qu, Z., Laviola, L., Ciccarone, A., Bistrian, B.R., Smith, R.J.
Growth hormone stimulates tyrosine phosphorylation of JAK2 and STAT5, but not insulin receptor substrate-1 or SHC proteins in liver and skeletal muscle of normal rats in vivo
(1996) Endocrinology, 137 (7), pp. 2880-2886.
Pacifico, F., Laviola, L., Ulianich, L., Porcellini, A., Ventra, C., Consiglio, E., Avvedimento, V.E.
Differential expression of the asyaloglycoprotein receptor in discrete brain areas, in kidney and thyroid
(1995) Biochemical and Biophysical Research Communications, 210 (1), pp. 138-144.
Porcellini, A., Ciullo, I., Laviola, L., Amabile, G., Fenzi, G., Awedimento, V.E.
Novel mutations of thyrotropin receptor gene in thyroid hyperfunctioning adenomas. Rapid identification by fine needle aspiration biopsy
(1994) Journal of Clinical Endocrinology and Metabolism, 79 (2), pp. 657-661.
Di Jeso, B., Laviola, L., Liguoro, D., Formisano, S., Consiglio, E.
P2 purinergic agonists and 12-O-tetradecanoylphorbol-13-acetate, as well as protein kinase A activators, stimulate thyroglobulin secretion in FRTL-5 cells
(1993) Biochemical and Biophysical Research Communications, 191 (2), pp. 385-391.